LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Seliciclib
10
uM
LJP5
 72
hr
 1657 2184 5588 0.3907 0.1692
BT-20 AT-7519
0.04
uM
LJP6
 72
hr
 1657 5115 5383 0.9511 0.9422
BT-20 AT-7519
0.12
uM
LJP6
 72
hr
 1657 4313 5383 0.8018 0.7564
BT-20 AT-7519
0.37
uM
LJP6
 72
hr
 1657 1889 5383 0.3511 0.0799
BT-20 AT-7519
1.11
uM
LJP6
 72
hr
 1657 1474 5383 0.2737 -0.0680
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1657 1217 5383 0.2261 -0.1671
BT-20 AT-7519
10
uM
LJP6
 72
hr
 1657 922 5383 0.1714 -0.2941
BT-20 AZD7762
0.04
uM
LJP6
 72
hr
 1657 5881 5383 1.0932 1.1076
BT-20 AZD7762
0.12
uM
LJP6
 72
hr
 1657 5352 5383 0.9954 0.9950
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1657 4158 5383 0.7729 0.7188
BT-20 AZD7762
1.11
uM
LJP6
 72
hr
 1657 2517 5383 0.4683 0.2793
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1657 1552 5383 0.2891 -0.0378
BT-20 AZD7762
10
uM
LJP6
 72
hr
 1657 836 5383 0.1552 -0.3321
BT-20 AZD8055
0.04
uM
LJP6
 72
hr
 1657 2584 5383 0.4793 0.2957
BT-20 AZD8055
0.12
uM
LJP6
 72
hr
 1657 2341 5383 0.4347 0.2245
BT-20 AZD8055
0.37
uM
LJP6
 72
hr
 1657 1984 5383 0.3689 0.1117
BT-20 AZD8055
1.11
uM
LJP6
 72
hr
 1657 1987 5383 0.3688 0.1108
BT-20 AZD8055
3.33
uM
LJP6
 72
hr
 1657 1826 5383 0.3392 0.0581
BT-20 AZD8055
10
uM
LJP6
 72
hr
 1657 1508 5383 0.2798 -0.0557
BT-20 Sorafenib
0.04
uM
LJP6
 72
hr
 1657 5122 5383 0.9509 0.9397
BT-20 Sorafenib
0.12
uM
LJP6
 72
hr
 1657 4954 5383 0.9204 0.9040
BT-20 Sorafenib
0.37
uM
LJP6
 72
hr
 1657 4847 5383 0.8995 0.8778
BT-20 Sorafenib
1.11
uM
LJP6
 72
hr
 1657 4723 5383 0.8775 0.8520
BT-20 Sorafenib
3.33
uM
LJP6
 72
hr
 1657 4606 5383 0.8551 0.8233
BT-20 Sorafenib
10
uM
LJP6
 72
hr
 1657 2825 5383 0.5241 0.3660