LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Radicicol
0.37
uM
LJP5
 72
hr
 868 1485 3410 0.4356 0.3123
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 868 1679 3556 0.4724 0.3830
MDA-MB-231 Radicicol
1.11
uM
LJP5
 72
hr
 868 1146 3410 0.3359 0.1501
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 868 1277 3556 0.3591 0.2086
MDA-MB-231 Radicicol
3.33
uM
LJP5
 72
hr
 868 1112 3410 0.3254 0.1305
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 868 1277 3556 0.3593 0.2090
MDA-MB-231 Radicicol
10
uM
LJP5
 72
hr
 868 1020 3410 0.2993 0.0850
MDA-MB-231 Radicicol
10
uM
LJP6
 72
hr
 868 1066 3556 0.2997 0.1058
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 72
hr
 868 3875 3410 1.1376 1.1350
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 72
hr
 868 3607 3556 1.0158 1.0156
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 72
hr
 868 3622 3410 1.0627 1.0630
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 72
hr
 868 3540 3556 0.9964 0.9967
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 72
hr
 868 2200 3410 0.6460 0.6025
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 72
hr
 868 1918 3556 0.5393 0.4761
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 72
hr
 868 936 3410 0.2750 0.0386
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 72
hr
 868 807 3556 0.2274 -0.0348
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 72
hr
 868 768 3410 0.2261 -0.0638
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 868 675 3556 0.1899 -0.1183
MDA-MB-231 Withaferin A
10
uM
LJP5
 72
hr
 868 476 3410 0.1396 -0.2634
MDA-MB-231 Withaferin A
10
uM
LJP6
 72
hr
 868 532 3556 0.1501 -0.2141
BT-20 Seliciclib
0.04
uM
LJP5
 72
hr
 1657 5718 5588 1.0234 1.0266
BT-20 Seliciclib
0.12
uM
LJP5
 72
hr
 1657 5585 5588 0.9996 0.9994
BT-20 Seliciclib
0.37
uM
LJP5
 72
hr
 1657 5212 5588 0.9328 0.9221
BT-20 Seliciclib
1.11
uM
LJP5
 72
hr
 1657 4763 5588 0.8525 0.8258
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1657 4547 5588 0.8139 0.7783