LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 BX-912
0.37
uM
LJP5
 72
hr
 1657 5456 5588 0.9766 0.9723
BT-20 BX-912
1.11
uM
LJP5
 72
hr
 1657 5160 5588 0.9238 0.9113
BT-20 BX-912
3.33
uM
LJP5
 72
hr
 1657 4240 5588 0.7587 0.7084
BT-20 BX-912
10
uM
LJP5
 72
hr
 1657 2697 5588 0.4828 0.3200
BT-20 Selumetinib
0.04
uM
LJP6
 72
hr
 1657 6126 5383 1.1379 1.1577
BT-20 Selumetinib
0.12
uM
LJP6
 72
hr
 1657 5592 5383 1.0401 1.0472
BT-20 Selumetinib
0.37
uM
LJP6
 72
hr
 1657 5683 5383 1.0577 1.0669
BT-20 Selumetinib
1.11
uM
LJP6
 72
hr
 1657 5734 5383 1.0660 1.0773
BT-20 Selumetinib
3.33
uM
LJP6
 72
hr
 1657 5739 5383 1.0667 1.0778
BT-20 Selumetinib
10
uM
LJP6
 72
hr
 1657 5417 5383 1.0075 1.0092
BT-20 MK2206
0.04
uM
LJP6
 72
hr
 1657 5368 5383 0.9970 0.9964
BT-20 MK2206
0.12
uM
LJP6
 72
hr
 1657 5029 5383 0.9349 0.9226
BT-20 MK2206
0.37
uM
LJP6
 72
hr
 1657 3982 5383 0.7392 0.6731
BT-20 MK2206
1.11
uM
LJP6
 72
hr
 1657 3538 5383 0.6576 0.5628
BT-20 MK2206
3.33
uM
LJP6
 72
hr
 1657 2935 5383 0.5449 0.3986
BT-20 MK2206
10
uM
LJP6
 72
hr
 1657 1838 5383 0.3415 0.0624
BT-20 AZD-6482
0.04
uM
LJP5
 72
hr
 1657 5328 5588 0.9536 0.9464
BT-20 AZD-6482
0.12
uM
LJP5
 72
hr
 1657 5004 5588 0.8954 0.8778
BT-20 AZD-6482
0.37
uM
LJP5
 72
hr
 1657 4328 5588 0.7746 0.7288
BT-20 AZD-6482
1.11
uM
LJP5
 72
hr
 1657 3514 5588 0.6289 0.5348
BT-20 AZD-6482
3.33
uM
LJP5
 72
hr
 1657 2461 5588 0.4405 0.2526
BT-20 AZD-6482
10
uM
LJP5
 72
hr
 1657 1556 5588 0.2787 -0.0353
BT-20 NU7441
0.04
uM
LJP5
 72
hr
 1657 5736 5588 1.0268 1.0302
BT-20 NU7441
0.12
uM
LJP5
 72
hr
 1657 5902 5588 1.0565 1.0634
BT-20 NU7441
0.37
uM
LJP5
 72
hr
 1657 5745 5588 1.0282 1.0320