LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 NU7441
1.11
uM
LJP5
 72
hr
 1657 5599 5588 1.0019 1.0015
BT-20 NU7441
3.33
uM
LJP5
 72
hr
 1657 5366 5588 0.9601 0.9534
BT-20 NU7441
10
uM
LJP5
 72
hr
 1657 2467 5588 0.4415 0.2543
BT-20 OSI-027
0.04
uM
LJP6
 72
hr
 1657 5567 5383 1.0327 1.0362
BT-20 OSI-027
0.12
uM
LJP6
 72
hr
 1657 4303 5383 0.7979 0.7485
BT-20 OSI-027
0.37
uM
LJP6
 72
hr
 1657 3446 5383 0.6390 0.5342
BT-20 OSI-027
1.11
uM
LJP6
 72
hr
 1657 2944 5383 0.5465 0.4008
BT-20 OSI-027
3.33
uM
LJP6
 72
hr
 1657 2599 5383 0.4819 0.2988
BT-20 OSI-027
10
uM
LJP6
 72
hr
 1657 2255 5383 0.4188 0.1965
BT-20 WYE-125132
0.04
uM
LJP6
 72
hr
 1657 3100 5383 0.5767 0.4464
BT-20 WYE-125132
0.12
uM
LJP6
 72
hr
 1657 2553 5383 0.4748 0.2899
BT-20 WYE-125132
0.37
uM
LJP6
 72
hr
 1657 2430 5383 0.4519 0.2530
BT-20 WYE-125132
1.11
uM
LJP6
 72
hr
 1657 2233 5383 0.4153 0.1920
BT-20 WYE-125132
3.33
uM
LJP6
 72
hr
 1657 2216 5383 0.4119 0.1865
BT-20 WYE-125132
10
uM
LJP6
 72
hr
 1657 2019 5383 0.3753 0.1232
BT-20 Barasertib
0.04
uM
LJP5
 72
hr
 1657 5249 5588 0.9396 0.9300
BT-20 Barasertib
0.12
uM
LJP5
 72
hr
 1657 4476 5588 0.8011 0.7621
BT-20 Barasertib
0.37
uM
LJP5
 72
hr
 1657 3393 5588 0.6072 0.5041
BT-20 Barasertib
1.11
uM
LJP5
 72
hr
 1657 2554 5588 0.4573 0.2792
BT-20 Barasertib
3.33
uM
LJP5
 72
hr
 1657 2292 5588 0.4103 0.2029
BT-20 Barasertib
10
uM
LJP5
 72
hr
 1657 1851 5588 0.3313 0.0649
BT-20 Vemurafenib
0.04
uM
LJP5
 72
hr
 1657 5732 5588 1.0264 1.0291
BT-20 Vemurafenib
0.12
uM
LJP5
 72
hr
 1657 5716 5588 1.0232 1.0263
BT-20 Vemurafenib
0.37
uM
LJP5
 72
hr
 1657 5543 5588 0.9918 0.9902
BT-20 Vemurafenib
1.11
uM
LJP5
 72
hr
 1657 5543 5588 0.9922 0.9910