LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Linsitinib
0.12
uM
LJP5
 72
hr
 1657 4955 5588 0.8869 0.8675
BT-20 Linsitinib
0.37
uM
LJP5
 72
hr
 1657 4992 5588 0.8935 0.8753
BT-20 Linsitinib
1.11
uM
LJP5
 72
hr
 1657 4955 5588 0.8867 0.8673
BT-20 Linsitinib
3.33
uM
LJP5
 72
hr
 1657 4834 5588 0.8654 0.8410
BT-20 Linsitinib
10
uM
LJP5
 72
hr
 1657 4391 5588 0.7856 0.7420
BT-20 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1657 5195 5588 0.9298 0.9185
BT-20 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1657 5224 5588 0.9350 0.9247
BT-20 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1657 5138 5588 0.9196 0.9066
BT-20 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1657 5047 5588 0.9033 0.8872
BT-20 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1657 4811 5588 0.8612 0.8366
BT-20 Ruxolitinib
10
uM
LJP5
 72
hr
 1657 3984 5588 0.7130 0.6490
BT-20 Momelotinib
0.04
uM
LJP5
 72
hr
 1657 4869 5588 0.8713 0.8475
BT-20 Momelotinib
0.12
uM
LJP5
 72
hr
 1657 4769 5588 0.8534 0.8269
BT-20 Momelotinib
0.37
uM
LJP5
 72
hr
 1657 4385 5588 0.7850 0.7418
BT-20 Momelotinib
1.11
uM
LJP5
 72
hr
 1657 4190 5588 0.7500 0.6972
BT-20 Momelotinib
3.33
uM
LJP5
 72
hr
 1657 3604 5588 0.6451 0.5573
BT-20 Momelotinib
10
uM
LJP5
 72
hr
 1657 2213 5588 0.3961 0.1791
BT-20 Fedratinib
0.04
uM
LJP5
 72
hr
 1657 5683 5588 1.0168 1.0185
BT-20 Fedratinib
0.12
uM
LJP5
 72
hr
 1657 5395 5588 0.9655 0.9603
BT-20 Fedratinib
0.37
uM
LJP5
 72
hr
 1657 5280 5588 0.9449 0.9362
BT-20 Fedratinib
1.11
uM
LJP5
 72
hr
 1657 4774 5588 0.8543 0.8280
BT-20 Fedratinib
3.33
uM
LJP5
 72
hr
 1657 3869 5588 0.6926 0.6219
BT-20 Fedratinib
10
uM
LJP5
 72
hr
 1657 1702 5588 0.3047 0.0148
BT-20 Trametinib
0.04
uM
LJP5
 72
hr
 1657 4042 5588 0.7233 0.6624
BT-20 Trametinib
0.12
uM
LJP5
 72
hr
 1657 4415 5588 0.7903 0.7484