LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset - HMS LINCS Database

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Small molecules	Cells

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Cell	Small Molecule	Small Mol Concentration	Small Mol Conc Unit	LJP Library Plate	Timepoint	Timepoint Unit	Mean Total Cell Count Before Treatment	Mean Total Cell Count After Treatment	Mean Total Control Cell Count	Mean Relative Cell Count	Mean Normalized Growth Rate Inhibition Value
BT-20	Trametinib	0.37	uM	LJP5	72	hr	1657	4368	5588	0.7815	0.7374
BT-20	Trametinib	1.11	uM	LJP5	72	hr	1657	4292	5588	0.7683	0.7202
BT-20	Trametinib	3.33	uM	LJP5	72	hr	1657	4154	5588	0.7436	0.6888
BT-20	Trametinib	10	uM	LJP5	72	hr	1657	4343	5588	0.7773	0.7322
BT-20	Omipalisib	0.04	uM	LJP6	72	hr	1657	1613	5383	0.2995	-0.0167
BT-20	Omipalisib	0.12	uM	LJP6	72	hr	1657	1438	5383	0.2668	-0.0816
BT-20	Omipalisib	0.37	uM	LJP6	72	hr	1657	1307	5383	0.2427	-0.1311
BT-20	Omipalisib	1.11	uM	LJP6	72	hr	1657	1187	5383	0.2209	-0.1783
BT-20	Omipalisib	3.33	uM	LJP6	72	hr	1657	1218	5383	0.2267	-0.1661
BT-20	Omipalisib	10	uM	LJP6	72	hr	1657	1130	5383	0.2100	-0.2022
BT-20	Buparlisib	0.04	uM	LJP5	72	hr	1657	5689	5588	1.0182	1.0202
BT-20	Buparlisib	0.12	uM	LJP5	72	hr	1657	5192	5588	0.9289	0.9173
BT-20	Buparlisib	0.37	uM	LJP5	72	hr	1657	3669	5588	0.6569	0.5736
BT-20	Buparlisib	1.11	uM	LJP5	72	hr	1657	1787	5588	0.3198	0.0436
BT-20	Buparlisib	3.33	uM	LJP5	72	hr	1657	1133	5588	0.2028	-0.1965
BT-20	Buparlisib	10	uM	LJP5	72	hr	1657	924	5588	0.1654	-0.2836
BT-20	XL147	0.04	uM	LJP5	72	hr	1657	5818	5588	1.0412	1.0466
BT-20	XL147	0.12	uM	LJP5	72	hr	1657	5761	5588	1.0311	1.0352
BT-20	XL147	0.37	uM	LJP5	72	hr	1657	5397	5588	0.9659	0.9608
BT-20	XL147	1.11	uM	LJP5	72	hr	1657	5265	5588	0.9421	0.9331
BT-20	XL147	3.33	uM	LJP5	72	hr	1657	4909	5588	0.8788	0.8578
BT-20	XL147	10	uM	LJP5	72	hr	1657	2185	5588	0.3911	0.1706
BT-20	Y39983	0.04	uM	LJP6	72	hr	1657	5418	5383	1.0069	1.0084
BT-20	Y39983	0.12	uM	LJP6	72	hr	1657	5340	5383	0.9930	0.9922
BT-20	Y39983	0.37	uM	LJP6	72	hr	1657	4915	5383	0.9130	0.8954

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HMS LINCS Project

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)