LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T HG-5-88-01
10
uM
LJP6
 72
hr
 929 2412 3216 0.7501 0.7035
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 929 3750 3216 1.1660 1.1789
Hs 578T HG-6-64-01
0.12
uM
LJP6
 72
hr
 929 3479 3216 1.0818 1.0895
Hs 578T HG-6-64-01
0.37
uM
LJP6
 72
hr
 929 2783 3216 0.8654 0.8449
Hs 578T HG-6-64-01
1.11
uM
LJP6
 72
hr
 929 1887 3216 0.5866 0.4848
Hs 578T HG-6-64-01
3.33
uM
LJP6
 72
hr
 929 1438 3216 0.4473 0.2760
Hs 578T HG-6-64-01
10
uM
LJP6
 72
hr
 929 682 3216 0.2120 -0.1590
Hs 578T Neratinib
0.04
uM
LJP5
 72
hr
 929 2920 3237 0.9022 0.8889
Hs 578T Neratinib
0.12
uM
LJP5
 72
hr
 929 2706 3237 0.8361 0.8106
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 929 2418 3237 0.7470 0.7008
Hs 578T Neratinib
1.11
uM
LJP5
 72
hr
 929 1952 3237 0.6032 0.5104
Hs 578T Neratinib
3.33
uM
LJP5
 72
hr
 929 1619 3237 0.5004 0.3616
Hs 578T Neratinib
10
uM
LJP5
 72
hr
 929 933 3237 0.2884 0.0024
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 929 3051 3216 0.9484 0.9415
Hs 578T JW-7-24-1
0.12
uM
LJP6
 72
hr
 929 2955 3216 0.9188 0.9077
Hs 578T JW-7-24-1
0.37
uM
LJP6
 72
hr
 929 2608 3216 0.8111 0.7794
Hs 578T JW-7-24-1
1.11
uM
LJP6
 72
hr
 929 2187 3216 0.6800 0.6126
Hs 578T JW-7-24-1
3.33
uM
LJP6
 72
hr
 929 1750 3216 0.5441 0.4239
Hs 578T JW-7-24-1
10
uM
LJP6
 72
hr
 929 864 3216 0.2685 -0.0419
Hs 578T Dasatinib
0.04
uM
LJP5
 72
hr
 929 2282 3237 0.7051 0.6472
Hs 578T Dasatinib
0.04
uM
LJP6
 72
hr
 929 1528 3216 0.4751 0.3198
Hs 578T Dasatinib
0.12
uM
LJP5
 72
hr
 929 1756 3237 0.5425 0.4240
Hs 578T Dasatinib
0.12
uM
LJP6
 72
hr
 929 1205 3216 0.3746 0.1556
Hs 578T Dasatinib
0.37
uM
LJP5
 72
hr
 929 1350 3237 0.4170 0.2297
Hs 578T Dasatinib
0.37
uM
LJP6
 72
hr
 929 1174 3216 0.3651 0.1393