LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dasatinib
1.11
uM
LJP5
 72
hr
 929 1283 3237 0.3964 0.1963
Hs 578T Dasatinib
1.11
uM
LJP6
 72
hr
 929 1201 3216 0.3736 0.1543
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 929 1290 3237 0.3987 0.1992
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 929 1040 3216 0.3235 0.0652
Hs 578T Dasatinib
10
uM
LJP5
 72
hr
 929 1142 3237 0.3529 0.1213
Hs 578T Dasatinib
10
uM
LJP6
 72
hr
 929 825 3216 0.2564 -0.0645
Hs 578T Tozasertib
0.04
uM
LJP5
 72
hr
 929 1399 3237 0.4321 0.2549
Hs 578T Tozasertib
0.12
uM
LJP5
 72
hr
 929 1299 3237 0.4015 0.2045
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 929 1386 3237 0.4282 0.2486
Hs 578T Tozasertib
1.11
uM
LJP5
 72
hr
 929 1283 3237 0.3963 0.1962
Hs 578T Tozasertib
3.33
uM
LJP5
 72
hr
 929 1367 3237 0.4224 0.2387
Hs 578T Tozasertib
10
uM
LJP5
 72
hr
 929 1127 3237 0.3484 0.1134
Hs 578T Imatinib
0.04
uM
LJP6
 72
hr
 929 3231 3216 1.0043 1.0047
Hs 578T Imatinib
0.12
uM
LJP6
 72
hr
 929 3189 3216 0.9913 0.9900
Hs 578T Imatinib
0.37
uM
LJP6
 72
hr
 929 3333 3216 1.0361 1.0400
Hs 578T Imatinib
1.11
uM
LJP6
 72
hr
 929 3363 3216 1.0455 1.0501
Hs 578T Imatinib
3.33
uM
LJP6
 72
hr
 929 3546 3216 1.1025 1.1120
Hs 578T Imatinib
10
uM
LJP6
 72
hr
 929 3625 3216 1.1269 1.1377
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 929 2877 3216 0.8946 0.8795
Hs 578T NVP-TAE684
0.12
uM
LJP6
 72
hr
 929 2015 3216 0.6265 0.5403
Hs 578T NVP-TAE684
0.37
uM
LJP6
 72
hr
 929 2237 3216 0.6955 0.6326
Hs 578T NVP-TAE684
1.11
uM
LJP6
 72
hr
 929 1773 3216 0.5514 0.4344
Hs 578T NVP-TAE684
3.33
uM
LJP6
 72
hr
 929 1207 3216 0.3753 0.1572
Hs 578T NVP-TAE684
10
uM
LJP6
 72
hr
 929 815 3216 0.2534 -0.0707
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 929 3045 3237 0.9404 0.9328