LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 929 | 3000 | 3237 | 0.9267 | 0.9173 |
Hs 578T | CP724714 | 10 | uM | LJP5 | 72 | hr | 929 | 2851 | 3237 | 0.8806 | 0.8635 |
Hs 578T | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 929 | 2245 | 3216 | 0.6982 | 0.6365 |
Hs 578T | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 929 | 852 | 3216 | 0.2649 | -0.0482 |
Hs 578T | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 929 | 734 | 3216 | 0.2284 | -0.1247 |
Hs 578T | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 929 | 764 | 3216 | 0.2376 | -0.1034 |
Hs 578T | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 929 | 751 | 3216 | 0.2335 | -0.1123 |
Hs 578T | Alvocidib | 10 | uM | LJP6 | 72 | hr | 929 | 814 | 3216 | 0.2532 | -0.0719 |
Hs 578T | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 929 | 3236 | 3216 | 1.0064 | 1.0071 |
Hs 578T | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 929 | 2312 | 3216 | 0.7193 | 0.6634 |
Hs 578T | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 929 | 1074 | 3216 | 0.3341 | 0.0844 |
Hs 578T | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 929 | 796 | 3216 | 0.2476 | -0.0825 |
Hs 578T | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 929 | 847 | 3216 | 0.2634 | -0.0509 |
Hs 578T | GW843682X | 10 | uM | LJP6 | 72 | hr | 929 | 1119 | 3216 | 0.3480 | 0.1086 |
Hs 578T | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3070 | 3237 | 0.9486 | 0.9423 |
Hs 578T | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 929 | 2910 | 3237 | 0.8990 | 0.8851 |
Hs 578T | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 929 | 2663 | 3237 | 0.8228 | 0.7947 |
Hs 578T | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 929 | 2102 | 3237 | 0.6495 | 0.5737 |
Hs 578T | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1400 | 3237 | 0.4328 | 0.2559 |
Hs 578T | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 929 | 995 | 3237 | 0.3076 | 0.0390 |
Hs 578T | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 929 | 3095 | 3216 | 0.9622 | 0.9575 |
Hs 578T | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 929 | 3045 | 3216 | 0.9467 | 0.9397 |
Hs 578T | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 929 | 2918 | 3216 | 0.9072 | 0.8942 |
Hs 578T | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 929 | 2823 | 3216 | 0.8777 | 0.8595 |
Hs 578T | HG-5-88-01 | 3.33 | uM | LJP6 | 72 | hr | 929 | 2708 | 3216 | 0.8420 | 0.8168 |