LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 929 1015 3216 0.3157 0.0506
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 929 853 3216 0.2653 -0.0466
Hs 578T AZD7762
10
uM
LJP6
 72
hr
 929 715 3216 0.2224 -0.1360
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 929 1457 3216 0.4532 0.2857
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 929 1326 3216 0.4123 0.2195
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 929 1276 3216 0.3969 0.1938
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 929 1254 3216 0.3901 0.1825
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 929 1264 3216 0.3929 0.1870
Hs 578T AZD8055
10
uM
LJP6
 72
hr
 929 1012 3216 0.3148 0.0486
Hs 578T Sorafenib
0.04
uM
LJP6
 72
hr
 929 3783 3216 1.1761 1.1895
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 929 3812 3216 1.1852 1.1991
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 929 3923 3216 1.2199 1.2347
Hs 578T Sorafenib
1.11
uM
LJP6
 72
hr
 929 4060 3216 1.2624 1.2779
Hs 578T Sorafenib
3.33
uM
LJP6
 72
hr
 929 3894 3216 1.2107 1.2253
Hs 578T Sorafenib
10
uM
LJP6
 72
hr
 929 3036 3216 0.9439 0.9364
Hs 578T CP466722
0.04
uM
LJP5
 72
hr
 929 3355 3237 1.0364 1.0400
Hs 578T CP466722
0.12
uM
LJP5
 72
hr
 929 3415 3237 1.0552 1.0606
Hs 578T CP466722
0.37
uM
LJP5
 72
hr
 929 3448 3237 1.0651 1.0713
Hs 578T CP466722
1.11
uM
LJP5
 72
hr
 929 3402 3237 1.0509 1.0560
Hs 578T CP466722
3.33
uM
LJP5
 72
hr
 929 3417 3237 1.0556 1.0610
Hs 578T CP466722
10
uM
LJP5
 72
hr
 929 2427 3237 0.7496 0.7038
Hs 578T CP724714
0.04
uM
LJP5
 72
hr
 929 3174 3237 0.9809 0.9787
Hs 578T CP724714
0.12
uM
LJP5
 72
hr
 929 3218 3237 0.9940 0.9932
Hs 578T CP724714
0.37
uM
LJP5
 72
hr
 929 3087 3237 0.9534 0.9473
Hs 578T CP724714
1.11
uM
LJP5
 72
hr
 929 3139 3237 0.9697 0.9660