LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 929 1340 3216 0.4164 0.2259
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 929 1338 3216 0.4160 0.2252
Hs 578T WYE-125132
1.11
uM
LJP6
 72
hr
 929 1280 3216 0.3980 0.1955
Hs 578T WYE-125132
3.33
uM
LJP6
 72
hr
 929 1331 3216 0.4138 0.2219
Hs 578T WYE-125132
10
uM
LJP6
 72
hr
 929 1265 3216 0.3933 0.1880
Hs 578T Barasertib
0.04
uM
LJP5
 72
hr
 929 1898 3237 0.5861 0.4859
Hs 578T Barasertib
0.12
uM
LJP5
 72
hr
 929 1883 3237 0.5817 0.4799
Hs 578T Barasertib
0.37
uM
LJP5
 72
hr
 929 1917 3237 0.5924 0.4954
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 929 1851 3237 0.5717 0.4660
Hs 578T Barasertib
3.33
uM
LJP5
 72
hr
 929 1684 3237 0.5205 0.3916
Hs 578T Barasertib
10
uM
LJP5
 72
hr
 929 1442 3237 0.4457 0.2762
Hs 578T Vemurafenib
0.04
uM
LJP5
 72
hr
 929 3317 3237 1.0246 1.0272
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 929 3356 3237 1.0368 1.0407
Hs 578T Vemurafenib
0.37
uM
LJP5
 72
hr
 929 3434 3237 1.0612 1.0671
Hs 578T Vemurafenib
1.11
uM
LJP5
 72
hr
 929 3362 3237 1.0388 1.0428
Hs 578T Vemurafenib
3.33
uM
LJP5
 72
hr
 929 2962 3237 0.9151 0.9038
Hs 578T Vemurafenib
10
uM
LJP5
 72
hr
 929 2051 3237 0.6337 0.5523
Hs 578T Enzastaurin
0.04
uM
LJP5
 72
hr
 929 3281 3237 1.0137 1.0151
Hs 578T Enzastaurin
0.12
uM
LJP5
 72
hr
 929 3263 3237 1.0082 1.0091
Hs 578T Enzastaurin
0.37
uM
LJP5
 72
hr
 929 3269 3237 1.0102 1.0113
Hs 578T Enzastaurin
1.11
uM
LJP5
 72
hr
 929 3280 3237 1.0134 1.0150
Hs 578T Enzastaurin
3.33
uM
LJP5
 72
hr
 929 3229 3237 0.9976 0.9971
Hs 578T Enzastaurin
10
uM
LJP5
 72
hr
 929 3070 3237 0.9484 0.9420
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 929 2313 3216 0.7191 0.6638
Hs 578T Palbociclib
0.12
uM
LJP6
 72
hr
 929 2019 3216 0.6278 0.5423