LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 929 2927 3216 0.9099 0.8973
Hs 578T MK2206
0.12
uM
LJP6
 72
hr
 929 2641 3216 0.8211 0.7914
Hs 578T MK2206
0.37
uM
LJP6
 72
hr
 929 1743 3216 0.5417 0.4200
Hs 578T MK2206
1.11
uM
LJP6
 72
hr
 929 2175 3216 0.6762 0.6074
Hs 578T MK2206
3.33
uM
LJP6
 72
hr
 929 2157 3216 0.6705 0.5997
Hs 578T MK2206
10
uM
LJP6
 72
hr
 929 1876 3216 0.5830 0.4787
Hs 578T AZD-6482
0.04
uM
LJP5
 72
hr
 929 3064 3237 0.9464 0.9395
Hs 578T AZD-6482
0.12
uM
LJP5
 72
hr
 929 2916 3237 0.9008 0.8869
Hs 578T AZD-6482
0.37
uM
LJP5
 72
hr
 929 2784 3237 0.8602 0.8395
Hs 578T AZD-6482
1.11
uM
LJP5
 72
hr
 929 2562 3237 0.7915 0.7562
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 929 2267 3237 0.7004 0.6412
Hs 578T AZD-6482
10
uM
LJP5
 72
hr
 929 1568 3237 0.4845 0.3371
Hs 578T NU7441
0.04
uM
LJP5
 72
hr
 929 3193 3237 0.9867 0.9852
Hs 578T NU7441
0.12
uM
LJP5
 72
hr
 929 3072 3237 0.9491 0.9428
Hs 578T NU7441
0.37
uM
LJP5
 72
hr
 929 2959 3237 0.9142 0.9028
Hs 578T NU7441
1.11
uM
LJP5
 72
hr
 929 2580 3237 0.7971 0.7633
Hs 578T NU7441
3.33
uM
LJP5
 72
hr
 929 2195 3237 0.6783 0.6121
Hs 578T NU7441
10
uM
LJP5
 72
hr
 929 1186 3237 0.3664 0.1449
Hs 578T OSI-027
0.04
uM
LJP6
 72
hr
 929 3225 3216 1.0027 1.0031
Hs 578T OSI-027
0.12
uM
LJP6
 72
hr
 929 3055 3216 0.9500 0.9436
Hs 578T OSI-027
0.37
uM
LJP6
 72
hr
 929 2403 3216 0.7473 0.6997
Hs 578T OSI-027
1.11
uM
LJP6
 72
hr
 929 1713 3216 0.5329 0.4073
Hs 578T OSI-027
3.33
uM
LJP6
 72
hr
 929 1500 3216 0.4665 0.3065
Hs 578T OSI-027
10
uM
LJP6
 72
hr
 929 1356 3216 0.4217 0.2344
Hs 578T WYE-125132
0.04
uM
LJP6
 72
hr
 929 1422 3216 0.4422 0.2681