LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Lapatinib
10
uM
LJP6
 72
hr
 929 2495 3216 0.7759 0.7352
Hs 578T Sirolimus
0.04
uM
LJP6
 72
hr
 929 2228 3216 0.6926 0.6286
Hs 578T Sirolimus
0.12
uM
LJP6
 72
hr
 929 2222 3216 0.6905 0.6252
Hs 578T Sirolimus
0.37
uM
LJP6
 72
hr
 929 2179 3216 0.6773 0.6083
Hs 578T Sirolimus
1.11
uM
LJP6
 72
hr
 929 2298 3216 0.7143 0.6570
Hs 578T Sirolimus
3.33
uM
LJP6
 72
hr
 929 2245 3216 0.6980 0.6363
Hs 578T Sirolimus
10
uM
LJP6
 72
hr
 929 2276 3216 0.7077 0.6489
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 929 2659 3216 0.8269 0.7986
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 929 2261 3216 0.7031 0.6429
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 929 1832 3216 0.5695 0.4605
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 929 1575 3216 0.4898 0.3426
Hs 578T ZSTK474
3.33
uM
LJP6
 72
hr
 929 1457 3216 0.4530 0.2853
Hs 578T ZSTK474
10
uM
LJP6
 72
hr
 929 1256 3216 0.3906 0.1829
Hs 578T BX-912
0.04
uM
LJP5
 72
hr
 929 3149 3237 0.9729 0.9697
Hs 578T BX-912
0.12
uM
LJP5
 72
hr
 929 3047 3237 0.9415 0.9343
Hs 578T BX-912
0.37
uM
LJP5
 72
hr
 929 2804 3237 0.8665 0.8470
Hs 578T BX-912
1.11
uM
LJP5
 72
hr
 929 1708 3237 0.5274 0.4014
Hs 578T BX-912
3.33
uM
LJP5
 72
hr
 929 1348 3237 0.4166 0.2297
Hs 578T BX-912
10
uM
LJP5
 72
hr
 929 934 3237 0.2887 0.0032
Hs 578T Selumetinib
0.04
uM
LJP6
 72
hr
 929 2018 3216 0.6274 0.5417
Hs 578T Selumetinib
0.12
uM
LJP6
 72
hr
 929 1796 3216 0.5583 0.4445
Hs 578T Selumetinib
0.37
uM
LJP6
 72
hr
 929 1748 3216 0.5434 0.4225
Hs 578T Selumetinib
1.11
uM
LJP6
 72
hr
 929 1707 3216 0.5307 0.4042
Hs 578T Selumetinib
3.33
uM
LJP6
 72
hr
 929 1651 3216 0.5133 0.3781
Hs 578T Selumetinib
10
uM
LJP6
 72
hr
 929 1501 3216 0.4666 0.3066