LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 929 3939 3237 1.2167 1.2301
Hs 578T SB590885
10
uM
LJP5
 72
hr
 929 2977 3237 0.9197 0.9092
Hs 578T Pictilisib
0.04
uM
LJP6
 72
hr
 929 2559 3216 0.7955 0.7601
Hs 578T Pictilisib
0.12
uM
LJP6
 72
hr
 929 2257 3216 0.7018 0.6413
Hs 578T Pictilisib
0.37
uM
LJP6
 72
hr
 929 1948 3216 0.6056 0.5115
Hs 578T Pictilisib
1.11
uM
LJP6
 72
hr
 929 1720 3216 0.5348 0.4102
Hs 578T Pictilisib
3.33
uM
LJP6
 72
hr
 929 1645 3216 0.5115 0.3752
Hs 578T Pictilisib
10
uM
LJP6
 72
hr
 929 1462 3216 0.4548 0.2882
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 929 2483 3237 0.7668 0.7254
Hs 578T PD184352
0.12
uM
LJP5
 72
hr
 929 2210 3237 0.6827 0.6179
Hs 578T PD184352
0.37
uM
LJP5
 72
hr
 929 2014 3237 0.6223 0.5367
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 929 1843 3237 0.5693 0.4628
Hs 578T PD184352
3.33
uM
LJP5
 72
hr
 929 1748 3237 0.5399 0.4199
Hs 578T PD184352
10
uM
LJP5
 72
hr
 929 1578 3237 0.4879 0.3420
Hs 578T PLX-4720
0.04
uM
LJP5
 72
hr
 929 3436 3237 1.0613 1.0670
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 929 3612 3237 1.1157 1.1250
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 929 3703 3237 1.1438 1.1546
Hs 578T PLX-4720
1.11
uM
LJP5
 72
hr
 929 3783 3237 1.1683 1.1803
Hs 578T PLX-4720
3.33
uM
LJP5
 72
hr
 929 3603 3237 1.1130 1.1224
Hs 578T PLX-4720
10
uM
LJP5
 72
hr
 929 2889 3237 0.8926 0.8775
Hs 578T Lapatinib
0.04
uM
LJP6
 72
hr
 929 3193 3216 0.9929 0.9920
Hs 578T Lapatinib
0.12
uM
LJP6
 72
hr
 929 3124 3216 0.9714 0.9679
Hs 578T Lapatinib
0.37
uM
LJP6
 72
hr
 929 3087 3216 0.9597 0.9546
Hs 578T Lapatinib
1.11
uM
LJP6
 72
hr
 929 3124 3216 0.9714 0.9678
Hs 578T Lapatinib
3.33
uM
LJP6
 72
hr
 929 3262 3216 1.0140 1.0155