LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Celastrol
0.37
uM
LJP6
 72
hr
 929 2735 3216 0.8503 0.8267
Hs 578T Celastrol
1.11
uM
LJP6
 72
hr
 929 1268 3216 0.3942 0.1892
Hs 578T Celastrol
3.33
uM
LJP6
 72
hr
 929 807 3216 0.2509 -0.0764
Hs 578T Celastrol
10
uM
LJP6
 72
hr
 929 564 3216 0.1754 -0.2459
Hs 578T SU11274
0.04
uM
LJP5
 72
hr
 929 3333 3237 1.0298 1.0329
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 929 3198 3237 0.9879 0.9866
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 929 3089 3237 0.9543 0.9487
Hs 578T SU11274
1.11
uM
LJP5
 72
hr
 929 2843 3237 0.8784 0.8611
Hs 578T SU11274
3.33
uM
LJP5
 72
hr
 929 2671 3237 0.8253 0.7977
Hs 578T SU11274
10
uM
LJP5
 72
hr
 929 1371 3237 0.4235 0.2411
Hs 578T Canertinib
0.04
uM
LJP6
 72
hr
 929 3209 3216 0.9979 0.9977
Hs 578T Canertinib
0.12
uM
LJP6
 72
hr
 929 3153 3216 0.9804 0.9780
Hs 578T Canertinib
0.37
uM
LJP6
 72
hr
 929 3123 3216 0.9710 0.9674
Hs 578T Canertinib
1.11
uM
LJP6
 72
hr
 929 3025 3216 0.9406 0.9327
Hs 578T Canertinib
3.33
uM
LJP6
 72
hr
 929 2707 3216 0.8418 0.8167
Hs 578T Canertinib
10
uM
LJP6
 72
hr
 929 609 3216 0.1895 -0.2097
Hs 578T NVP-AEW541
0.04
uM
LJP5
 72
hr
 929 3371 3237 1.0415 1.0458
Hs 578T NVP-AEW541
0.12
uM
LJP5
 72
hr
 929 3327 3237 1.0280 1.0309
Hs 578T NVP-AEW541
0.37
uM
LJP5
 72
hr
 929 3308 3237 1.0221 1.0245
Hs 578T NVP-AEW541
1.11
uM
LJP5
 72
hr
 929 3290 3237 1.0164 1.0183
Hs 578T NVP-AEW541
3.33
uM
LJP5
 72
hr
 929 3287 3237 1.0154 1.0170
Hs 578T NVP-AEW541
10
uM
LJP5
 72
hr
 929 1693 3237 0.5229 0.3950
Hs 578T PHA-665752
0.04
uM
LJP5
 72
hr
 929 3287 3237 1.0154 1.0169
Hs 578T PHA-665752
0.12
uM
LJP5
 72
hr
 929 3242 3237 1.0017 1.0019
Hs 578T PHA-665752
0.37
uM
LJP5
 72
hr
 929 3263 3237 1.0080 1.0088