LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T PHA-665752
1.11
uM
LJP5
 72
hr
 929 3174 3237 0.9805 0.9782
Hs 578T PHA-665752
3.33
uM
LJP5
 72
hr
 929 3151 3237 0.9737 0.9707
Hs 578T PHA-665752
10
uM
LJP5
 72
hr
 929 1974 3237 0.6086 0.5084
Hs 578T PI103
0.04
uM
LJP6
 72
hr
 929 2243 3216 0.6975 0.6356
Hs 578T PI103
0.12
uM
LJP6
 72
hr
 929 1583 3216 0.4923 0.3464
Hs 578T PI103
0.37
uM
LJP6
 72
hr
 929 1354 3216 0.4211 0.2342
Hs 578T PI103
1.11
uM
LJP6
 72
hr
 929 1298 3216 0.4036 0.2052
Hs 578T PI103
3.33
uM
LJP6
 72
hr
 929 1285 3216 0.3995 0.1983
Hs 578T PI103
10
uM
LJP6
 72
hr
 929 1293 3216 0.4019 0.2020
Hs 578T Dovitinib
0.04
uM
LJP5
 72
hr
 929 2551 3237 0.7879 0.7515
Hs 578T Dovitinib
0.12
uM
LJP5
 72
hr
 929 2026 3237 0.6258 0.5411
Hs 578T Dovitinib
0.37
uM
LJP5
 72
hr
 929 1674 3237 0.5171 0.3866
Hs 578T Dovitinib
1.11
uM
LJP5
 72
hr
 929 1655 3237 0.5115 0.3782
Hs 578T Dovitinib
3.33
uM
LJP5
 72
hr
 929 1637 3237 0.5058 0.3692
Hs 578T Dovitinib
10
uM
LJP5
 72
hr
 929 1758 3237 0.5430 0.4244
Hs 578T GSK 690693
0.04
uM
LJP5
 72
hr
 929 2630 3237 0.8127 0.7822
Hs 578T GSK 690693
0.12
uM
LJP5
 72
hr
 929 2504 3237 0.7734 0.7339
Hs 578T GSK 690693
0.37
uM
LJP5
 72
hr
 929 2343 3237 0.7237 0.6711
Hs 578T GSK 690693
1.11
uM
LJP5
 72
hr
 929 2291 3237 0.7076 0.6497
Hs 578T GSK 690693
3.33
uM
LJP5
 72
hr
 929 2298 3237 0.7097 0.6529
Hs 578T GSK 690693
10
uM
LJP5
 72
hr
 929 2363 3237 0.7299 0.6790
Hs 578T SNS-032
0.04
uM
LJP6
 72
hr
 929 2686 3216 0.8351 0.8086
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 929 868 3216 0.2700 -0.0375
Hs 578T SNS-032
0.37
uM
LJP6
 72
hr
 929 784 3216 0.2438 -0.0916
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 929 769 3216 0.2390 -0.1006