LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 513 10401 10473 0.9931 0.9965
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 513 10330 10473 0.9863 0.9936
MCF 10A Sorafenib
1.11
uM
LJP6
 72
hr
 513 10318 10473 0.9853 0.9927
MCF 10A Sorafenib
3.33
uM
LJP6
 72
hr
 513 10151 10473 0.9694 0.9856
MCF 10A Sorafenib
10
uM
LJP6
 72
hr
 513 5955 10473 0.5687 0.7566
MCF 10A CP466722
0.04
uM
LJP5
 72
hr
 513 10852 10362 1.0473 1.0214
MCF 10A CP466722
0.12
uM
LJP5
 72
hr
 513 10964 10362 1.0581 1.0262
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 513 10725 10362 1.0350 1.0159
MCF 10A CP466722
1.11
uM
LJP5
 72
hr
 513 10141 10362 0.9789 0.9898
MCF 10A CP466722
3.33
uM
LJP5
 72
hr
 513 9517 10362 0.9184 0.9609
MCF 10A CP466722
10
uM
LJP5
 72
hr
 513 2844 10362 0.2745 0.4811
MCF 10A CP724714
0.04
uM
LJP5
 72
hr
 513 10600 10362 1.0224 1.0094
MCF 10A CP724714
0.12
uM
LJP5
 72
hr
 513 10313 10362 0.9951 0.9976
MCF 10A CP724714
0.37
uM
LJP5
 72
hr
 513 10181 10362 0.9824 0.9917
MCF 10A CP724714
1.11
uM
LJP5
 72
hr
 513 10075 10362 0.9722 0.9870
MCF 10A CP724714
3.33
uM
LJP5
 72
hr
 513 10064 10362 0.9712 0.9866
MCF 10A CP724714
10
uM
LJP5
 72
hr
 513 9029 10362 0.8713 0.9373
MCF 10A Alvocidib
0.04
uM
LJP6
 72
hr
 513 1211 10473 0.1157 0.2180
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 513 486 10473 0.0464 -0.0146
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 513 452 10473 0.0432 -0.0298
MCF 10A Alvocidib
1.11
uM
LJP6
 72
hr
 513 476 10473 0.0455 -0.0173
MCF 10A Alvocidib
3.33
uM
LJP6
 72
hr
 513 505 10473 0.0482 -0.0038
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 513 467 10473 0.0447 -0.0214
MCF 10A GW843682X
0.04
uM
LJP6
 72
hr
 513 9055 10473 0.8647 0.9335
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 513 6501 10473 0.6206 0.7920