LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Barasertib
10
uM
LJP5
 72
hr
 513 1307 10362 0.1261 0.2403
MCF 10A Vemurafenib
0.04
uM
LJP5
 72
hr
 513 10043 10362 0.9691 0.9853
MCF 10A Vemurafenib
0.12
uM
LJP5
 72
hr
 513 10275 10362 0.9915 0.9960
MCF 10A Vemurafenib
0.37
uM
LJP5
 72
hr
 513 9959 10362 0.9608 0.9814
MCF 10A Vemurafenib
1.11
uM
LJP5
 72
hr
 513 8358 10362 0.8066 0.9032
MCF 10A Vemurafenib
3.33
uM
LJP5
 72
hr
 513 4431 10362 0.4271 0.6410
MCF 10A Vemurafenib
10
uM
LJP5
 72
hr
 513 1903 10362 0.1836 0.3524
MCF 10A Enzastaurin
0.04
uM
LJP5
 72
hr
 513 10269 10362 0.9908 0.9954
MCF 10A Enzastaurin
0.12
uM
LJP5
 72
hr
 513 10051 10362 0.9698 0.9857
MCF 10A Enzastaurin
0.37
uM
LJP5
 72
hr
 513 9980 10362 0.9629 0.9825
MCF 10A Enzastaurin
1.11
uM
LJP5
 72
hr
 513 10017 10362 0.9663 0.9838
MCF 10A Enzastaurin
3.33
uM
LJP5
 72
hr
 513 9146 10362 0.8823 0.9423
MCF 10A Enzastaurin
10
uM
LJP5
 72
hr
 513 7625 10362 0.7357 0.8632
MCF 10A Palbociclib
0.04
uM
LJP6
 72
hr
 513 7760 10473 0.7410 0.8668
MCF 10A Palbociclib
0.12
uM
LJP6
 72
hr
 513 6252 10473 0.5969 0.7762
MCF 10A Palbociclib
0.37
uM
LJP6
 72
hr
 513 4868 10473 0.4647 0.6768
MCF 10A Palbociclib
1.11
uM
LJP6
 72
hr
 513 3769 10473 0.3599 0.5813
MCF 10A Palbociclib
3.33
uM
LJP6
 72
hr
 513 3336 10473 0.3184 0.5371
MCF 10A Palbociclib
10
uM
LJP6
 72
hr
 513 2395 10473 0.2286 0.4244
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 513 8702 10473 0.8310 0.9167
MCF 10A PF562271
0.12
uM
LJP6
 72
hr
 513 7123 10473 0.6802 0.8304
MCF 10A PF562271
0.37
uM
LJP6
 72
hr
 513 4631 10473 0.4421 0.6568
MCF 10A PF562271
1.11
uM
LJP6
 72
hr
 513 1722 10473 0.1644 0.3177
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 513 668 10473 0.0638 0.0620
MCF 10A PF562271
10
uM
LJP6
 72
hr
 513 589 10473 0.0563 0.0322