LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD-6482
3.33
uM
LJP5
 72
hr
 513 4932 10362 0.4762 0.6849
MCF 10A AZD-6482
10
uM
LJP5
 72
hr
 513 773 10362 0.0746 0.0979
MCF 10A NU7441
0.04
uM
LJP5
 72
hr
 513 10965 10362 1.0578 1.0258
MCF 10A NU7441
0.12
uM
LJP5
 72
hr
 513 10405 10362 1.0039 1.0016
MCF 10A NU7441
0.37
uM
LJP5
 72
hr
 513 10085 10362 0.9728 0.9868
MCF 10A NU7441
1.11
uM
LJP5
 72
hr
 513 9249 10362 0.8925 0.9481
MCF 10A NU7441
3.33
uM
LJP5
 72
hr
 513 7796 10362 0.7522 0.8728
MCF 10A NU7441
10
uM
LJP5
 72
hr
 513 1002 10362 0.0967 0.1650
MCF 10A OSI-027
0.04
uM
LJP6
 72
hr
 513 7223 10473 0.6898 0.8353
MCF 10A OSI-027
0.12
uM
LJP6
 72
hr
 513 3642 10473 0.3476 0.5655
MCF 10A OSI-027
0.37
uM
LJP6
 72
hr
 513 2270 10473 0.2167 0.4065
MCF 10A OSI-027
1.11
uM
LJP6
 72
hr
 513 1313 10473 0.1253 0.2390
MCF 10A OSI-027
3.33
uM
LJP6
 72
hr
 513 1101 10473 0.1052 0.1917
MCF 10A OSI-027
10
uM
LJP6
 72
hr
 513 838 10473 0.0800 0.1175
MCF 10A WYE-125132
0.04
uM
LJP6
 72
hr
 513 2567 10473 0.2451 0.4474
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 513 1471 10473 0.1404 0.2736
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 513 1303 10473 0.1245 0.2383
MCF 10A WYE-125132
1.11
uM
LJP6
 72
hr
 513 1041 10473 0.0994 0.1758
MCF 10A WYE-125132
3.33
uM
LJP6
 72
hr
 513 896 10473 0.0856 0.1366
MCF 10A WYE-125132
10
uM
LJP6
 72
hr
 513 882 10473 0.0841 0.1290
MCF 10A Barasertib
0.04
uM
LJP5
 72
hr
 513 1407 10362 0.1358 0.2617
MCF 10A Barasertib
0.12
uM
LJP5
 72
hr
 513 1333 10362 0.1287 0.2459
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 513 1313 10362 0.1268 0.2419
MCF 10A Barasertib
1.11
uM
LJP5
 72
hr
 513 1268 10362 0.1224 0.2319
MCF 10A Barasertib
3.33
uM
LJP5
 72
hr
 513 1376 10362 0.1328 0.2553