LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A ZSTK474
1.11
uM
LJP6
 72
hr
 513 2117 10473 0.2022 0.3838
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 513 1435 10473 0.1370 0.2649
MCF 10A ZSTK474
10
uM
LJP6
 72
hr
 513 1292 10473 0.1234 0.2346
MCF 10A BX-912
0.04
uM
LJP5
 72
hr
 513 9307 10362 0.8981 0.9510
MCF 10A BX-912
0.12
uM
LJP5
 72
hr
 513 9452 10362 0.9123 0.9580
MCF 10A BX-912
0.37
uM
LJP5
 72
hr
 513 6485 10362 0.6257 0.7947
MCF 10A BX-912
1.11
uM
LJP5
 72
hr
 513 1516 10362 0.1463 0.2837
MCF 10A BX-912
3.33
uM
LJP5
 72
hr
 513 1326 10362 0.1280 0.2446
MCF 10A BX-912
10
uM
LJP5
 72
hr
 513 957 10362 0.0924 0.1545
MCF 10A Selumetinib
0.04
uM
LJP6
 72
hr
 513 3659 10473 0.3493 0.5698
MCF 10A Selumetinib
0.12
uM
LJP6
 72
hr
 513 2200 10473 0.2101 0.3970
MCF 10A Selumetinib
0.37
uM
LJP6
 72
hr
 513 1629 10473 0.1556 0.3035
MCF 10A Selumetinib
1.11
uM
LJP6
 72
hr
 513 1235 10473 0.1180 0.2216
MCF 10A Selumetinib
3.33
uM
LJP6
 72
hr
 513 1150 10473 0.1099 0.2029
MCF 10A Selumetinib
10
uM
LJP6
 72
hr
 513 900 10473 0.0859 0.1359
MCF 10A MK2206
0.04
uM
LJP6
 72
hr
 513 10448 10473 0.9975 0.9988
MCF 10A MK2206
0.12
uM
LJP6
 72
hr
 513 9837 10473 0.9391 0.9710
MCF 10A MK2206
0.37
uM
LJP6
 72
hr
 513 2813 10473 0.2686 0.4782
MCF 10A MK2206
1.11
uM
LJP6
 72
hr
 513 7275 10473 0.6944 0.8388
MCF 10A MK2206
3.33
uM
LJP6
 72
hr
 513 6006 10473 0.5734 0.7590
MCF 10A MK2206
10
uM
LJP6
 72
hr
 513 2063 10473 0.1970 0.3767
MCF 10A AZD-6482
0.04
uM
LJP5
 72
hr
 513 9739 10362 0.9398 0.9714
MCF 10A AZD-6482
0.12
uM
LJP5
 72
hr
 513 8086 10362 0.7804 0.8883
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 513 7846 10362 0.7567 0.8747
MCF 10A AZD-6482
1.11
uM
LJP5
 72
hr
 513 6398 10362 0.6170 0.7879