LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Dovitinib
0.12
uM
LJP5
 72
hr
 513 7328 10362 0.7074 0.8463
MCF 10A Dovitinib
0.37
uM
LJP5
 72
hr
 513 3966 10362 0.3832 0.6011
MCF 10A Dovitinib
1.11
uM
LJP5
 72
hr
 513 2212 10362 0.2135 0.4000
MCF 10A Dovitinib
3.33
uM
LJP5
 72
hr
 513 1073 10362 0.1036 0.1761
MCF 10A Dovitinib
10
uM
LJP5
 72
hr
 513 652 10362 0.0627 0.0414
MCF 10A GSK 690693
0.04
uM
LJP5
 72
hr
 513 9415 10362 0.9088 0.9561
MCF 10A GSK 690693
0.12
uM
LJP5
 72
hr
 513 9574 10362 0.9242 0.9635
MCF 10A GSK 690693
0.37
uM
LJP5
 72
hr
 513 9016 10362 0.8702 0.9363
MCF 10A GSK 690693
1.11
uM
LJP5
 72
hr
 513 7238 10362 0.6984 0.8408
MCF 10A GSK 690693
3.33
uM
LJP5
 72
hr
 513 7222 10362 0.6966 0.8394
MCF 10A GSK 690693
10
uM
LJP5
 72
hr
 513 7361 10362 0.7104 0.8482
MCF 10A SNS-032
0.04
uM
LJP6
 72
hr
 513 6891 10473 0.6577 0.8158
MCF 10A SNS-032
0.12
uM
LJP6
 72
hr
 513 662 10473 0.0632 0.0586
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 513 549 10473 0.0524 0.0155
MCF 10A SNS-032
1.11
uM
LJP6
 72
hr
 513 486 10473 0.0464 -0.0145
MCF 10A SNS-032
3.33
uM
LJP6
 72
hr
 513 488 10473 0.0466 -0.0119
MCF 10A SNS-032
10
uM
LJP6
 72
hr
 513 407 10473 0.0389 -0.0534
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 513 351 10473 0.0335 -0.0847
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 513 427 10473 0.0408 -0.0420
MCF 10A Afatinib
0.37
uM
LJP6
 72
hr
 513 487 10473 0.0465 -0.0133
MCF 10A Afatinib
1.11
uM
LJP6
 72
hr
 513 588 10473 0.0562 0.0319
MCF 10A Afatinib
3.33
uM
LJP6
 72
hr
 513 525 10473 0.0502 0.0048
MCF 10A Afatinib
10
uM
LJP6
 72
hr
 513 561 10473 0.0536 0.0195
MCF 10A GSK1904529A
0.04
uM
LJP6
 72
hr
 513 3073 10473 0.2931 0.5040
MCF 10A GSK1904529A
0.12
uM
LJP6
 72
hr
 513 3050 10473 0.2910 0.5025