LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 513 | 2532 | 10473 | 0.2417 | 0.4426 |
MCF 10A | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 513 | 2029 | 10473 | 0.1936 | 0.3695 |
MCF 10A | GSK1904529A | 3.33 | uM | LJP6 | 72 | hr | 513 | 2209 | 10473 | 0.2109 | 0.3976 |
MCF 10A | GSK1904529A | 10 | uM | LJP6 | 72 | hr | 513 | 2684 | 10473 | 0.2562 | 0.4617 |
MCF 10A | Linsitinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 8348 | 10362 | 0.8056 | 0.9027 |
MCF 10A | Linsitinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 7087 | 10362 | 0.6844 | 0.8318 |
MCF 10A | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 513 | 4475 | 10362 | 0.4321 | 0.6467 |
MCF 10A | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 3861 | 10362 | 0.3727 | 0.5928 |
MCF 10A | Linsitinib | 3.33 | uM | LJP5 | 72 | hr | 513 | 3084 | 10362 | 0.2979 | 0.5113 |
MCF 10A | Linsitinib | 10 | uM | LJP5 | 72 | hr | 513 | 2013 | 10362 | 0.1943 | 0.3701 |
MCF 10A | Ruxolitinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 9769 | 10362 | 0.9427 | 0.9730 |
MCF 10A | Ruxolitinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 10005 | 10362 | 0.9654 | 0.9837 |
MCF 10A | Ruxolitinib | 0.37 | uM | LJP5 | 72 | hr | 513 | 9609 | 10362 | 0.9275 | 0.9654 |
MCF 10A | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 8960 | 10362 | 0.8647 | 0.9339 |
MCF 10A | Ruxolitinib | 3.33 | uM | LJP5 | 72 | hr | 513 | 8789 | 10362 | 0.8483 | 0.9251 |
MCF 10A | Ruxolitinib | 10 | uM | LJP5 | 72 | hr | 513 | 6672 | 10362 | 0.6443 | 0.8063 |
MCF 10A | Momelotinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 8973 | 10362 | 0.8663 | 0.9345 |
MCF 10A | Momelotinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 8077 | 10362 | 0.7794 | 0.8882 |
MCF 10A | Momelotinib | 0.37 | uM | LJP5 | 72 | hr | 513 | 6977 | 10362 | 0.6731 | 0.8253 |
MCF 10A | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 5846 | 10362 | 0.5641 | 0.7524 |
MCF 10A | Momelotinib | 3.33 | uM | LJP5 | 72 | hr | 513 | 4328 | 10362 | 0.4175 | 0.6343 |
MCF 10A | Momelotinib | 10 | uM | LJP5 | 72 | hr | 513 | 1580 | 10362 | 0.1524 | 0.2944 |
MCF 10A | Fedratinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 10336 | 10362 | 0.9976 | 0.9989 |
MCF 10A | Fedratinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 9869 | 10362 | 0.9525 | 0.9775 |
MCF 10A | Fedratinib | 0.37 | uM | LJP5 | 72 | hr | 513 | 9475 | 10362 | 0.9146 | 0.9591 |