LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GSK1904529A
0.37
uM
LJP6
72
hr
513 2532 10473 0.2417 0.4426
MCF 10A GSK1904529A
1.11
uM
LJP6
72
hr
513 2029 10473 0.1936 0.3695
MCF 10A GSK1904529A
3.33
uM
LJP6
72
hr
513 2209 10473 0.2109 0.3976
MCF 10A GSK1904529A
10
uM
LJP6
72
hr
513 2684 10473 0.2562 0.4617
MCF 10A Linsitinib
0.04
uM
LJP5
72
hr
513 8348 10362 0.8056 0.9027
MCF 10A Linsitinib
0.12
uM
LJP5
72
hr
513 7087 10362 0.6844 0.8318
MCF 10A Linsitinib
0.37
uM
LJP5
72
hr
513 4475 10362 0.4321 0.6467
MCF 10A Linsitinib
1.11
uM
LJP5
72
hr
513 3861 10362 0.3727 0.5928
MCF 10A Linsitinib
3.33
uM
LJP5
72
hr
513 3084 10362 0.2979 0.5113
MCF 10A Linsitinib
10
uM
LJP5
72
hr
513 2013 10362 0.1943 0.3701
MCF 10A Ruxolitinib
0.04
uM
LJP5
72
hr
513 9769 10362 0.9427 0.9730
MCF 10A Ruxolitinib
0.12
uM
LJP5
72
hr
513 10005 10362 0.9654 0.9837
MCF 10A Ruxolitinib
0.37
uM
LJP5
72
hr
513 9609 10362 0.9275 0.9654
MCF 10A Ruxolitinib
1.11
uM
LJP5
72
hr
513 8960 10362 0.8647 0.9339
MCF 10A Ruxolitinib
3.33
uM
LJP5
72
hr
513 8789 10362 0.8483 0.9251
MCF 10A Ruxolitinib
10
uM
LJP5
72
hr
513 6672 10362 0.6443 0.8063
MCF 10A Momelotinib
0.04
uM
LJP5
72
hr
513 8973 10362 0.8663 0.9345
MCF 10A Momelotinib
0.12
uM
LJP5
72
hr
513 8077 10362 0.7794 0.8882
MCF 10A Momelotinib
0.37
uM
LJP5
72
hr
513 6977 10362 0.6731 0.8253
MCF 10A Momelotinib
1.11
uM
LJP5
72
hr
513 5846 10362 0.5641 0.7524
MCF 10A Momelotinib
3.33
uM
LJP5
72
hr
513 4328 10362 0.4175 0.6343
MCF 10A Momelotinib
10
uM
LJP5
72
hr
513 1580 10362 0.1524 0.2944
MCF 10A Fedratinib
0.04
uM
LJP5
72
hr
513 10336 10362 0.9976 0.9989
MCF 10A Fedratinib
0.12
uM
LJP5
72
hr
513 9869 10362 0.9525 0.9775
MCF 10A Fedratinib
0.37
uM
LJP5
72
hr
513 9475 10362 0.9146 0.9591