LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PD184352
0.37
uM
LJP5
 72
hr
 513 2140 10362 0.2067 0.3895
MCF 10A PD184352
1.11
uM
LJP5
 72
hr
 513 1543 10362 0.1490 0.2875
MCF 10A PD184352
3.33
uM
LJP5
 72
hr
 513 1165 10362 0.1124 0.2079
MCF 10A PD184352
10
uM
LJP5
 72
hr
 513 781 10362 0.0754 0.1018
MCF 10A PLX-4720
0.04
uM
LJP5
 72
hr
 513 10627 10362 1.0254 1.0115
MCF 10A PLX-4720
0.12
uM
LJP5
 72
hr
 513 10983 10362 1.0602 1.0270
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 513 11131 10362 1.0743 1.0333
MCF 10A PLX-4720
1.11
uM
LJP5
 72
hr
 513 11521 10362 1.1122 1.0495
MCF 10A PLX-4720
3.33
uM
LJP5
 72
hr
 513 10721 10362 1.0349 1.0157
MCF 10A PLX-4720
10
uM
LJP5
 72
hr
 513 7135 10362 0.6888 0.8350
MCF 10A Lapatinib
0.04
uM
LJP6
 72
hr
 513 9294 10473 0.8875 0.9459
MCF 10A Lapatinib
0.12
uM
LJP6
 72
hr
 513 8925 10473 0.8523 0.9278
MCF 10A Lapatinib
0.37
uM
LJP6
 72
hr
 513 8542 10473 0.8157 0.9085
MCF 10A Lapatinib
1.11
uM
LJP6
 72
hr
 513 6980 10473 0.6666 0.8219
MCF 10A Lapatinib
3.33
uM
LJP6
 72
hr
 513 3620 10473 0.3456 0.5665
MCF 10A Lapatinib
10
uM
LJP6
 72
hr
 513 770 10473 0.0735 0.0953
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 513 9497 10473 0.9067 0.9553
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 513 10290 10473 0.9828 0.9917
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 513 10033 10473 0.9580 0.9803
MCF 10A Sirolimus
1.11
uM
LJP6
 72
hr
 513 10098 10473 0.9641 0.9832
MCF 10A Sirolimus
3.33
uM
LJP6
 72
hr
 513 10271 10473 0.9808 0.9909
MCF 10A Sirolimus
10
uM
LJP6
 72
hr
 513 9940 10473 0.9489 0.9756
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 513 7992 10473 0.7632 0.8793
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 513 5213 10473 0.4976 0.7027
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 513 3122 10473 0.2980 0.5140