LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 929 | 1177 | 3237 | 0.3635 | 0.1399 |
Hs 578T | Dactolisib | 10 | uM | LJP5 | 72 | hr | 929 | 1181 | 3237 | 0.3652 | 0.1428 |
Hs 578T | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 929 | 3166 | 3237 | 0.9778 | 0.9750 |
Hs 578T | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 929 | 2991 | 3237 | 0.9241 | 0.9141 |
Hs 578T | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 929 | 2926 | 3237 | 0.9040 | 0.8910 |
Hs 578T | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 929 | 2851 | 3237 | 0.8808 | 0.8638 |
Hs 578T | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 929 | 2563 | 3237 | 0.7918 | 0.7567 |
Hs 578T | Alpelisib | 10 | uM | LJP5 | 72 | hr | 929 | 2115 | 3237 | 0.6534 | 0.5789 |
Hs 578T | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 929 | 2406 | 3237 | 0.7433 | 0.6962 |
Hs 578T | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 929 | 1782 | 3237 | 0.5506 | 0.4357 |
Hs 578T | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 929 | 1451 | 3237 | 0.4483 | 0.2809 |
Hs 578T | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 929 | 1341 | 3237 | 0.4143 | 0.2260 |
Hs 578T | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1311 | 3237 | 0.4052 | 0.2109 |
Hs 578T | GDC-0980 | 10 | uM | LJP5 | 72 | hr | 929 | 1198 | 3237 | 0.3704 | 0.1512 |
Hs 578T | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 929 | 1292 | 3237 | 0.3993 | 0.2006 |
Hs 578T | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 929 | 1329 | 3216 | 0.4131 | 0.2207 |
Hs 578T | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 929 | 1017 | 3237 | 0.3142 | 0.0505 |
Hs 578T | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 929 | 941 | 3216 | 0.2927 | 0.0072 |
Hs 578T | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 929 | 935 | 3237 | 0.2888 | 0.0032 |
Hs 578T | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 929 | 894 | 3216 | 0.2779 | -0.0215 |
Hs 578T | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 929 | 774 | 3237 | 0.2391 | -0.0973 |
Hs 578T | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 929 | 775 | 3216 | 0.2407 | -0.0987 |
Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 929 | 530 | 3237 | 0.1639 | -0.2678 |
Hs 578T | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 929 | 550 | 3216 | 0.1711 | -0.2542 |
Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 929 | 442 | 3237 | 0.1366 | -0.3389 |