LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dactolisib
3.33
uM
LJP5
72
hr
929 1177 3237 0.3635 0.1399
Hs 578T Dactolisib
10
uM
LJP5
72
hr
929 1181 3237 0.3652 0.1428
Hs 578T Alpelisib
0.04
uM
LJP5
72
hr
929 3166 3237 0.9778 0.9750
Hs 578T Alpelisib
0.12
uM
LJP5
72
hr
929 2991 3237 0.9241 0.9141
Hs 578T Alpelisib
0.37
uM
LJP5
72
hr
929 2926 3237 0.9040 0.8910
Hs 578T Alpelisib
1.11
uM
LJP5
72
hr
929 2851 3237 0.8808 0.8638
Hs 578T Alpelisib
3.33
uM
LJP5
72
hr
929 2563 3237 0.7918 0.7567
Hs 578T Alpelisib
10
uM
LJP5
72
hr
929 2115 3237 0.6534 0.5789
Hs 578T GDC-0980
0.04
uM
LJP5
72
hr
929 2406 3237 0.7433 0.6962
Hs 578T GDC-0980
0.12
uM
LJP5
72
hr
929 1782 3237 0.5506 0.4357
Hs 578T GDC-0980
0.37
uM
LJP5
72
hr
929 1451 3237 0.4483 0.2809
Hs 578T GDC-0980
1.11
uM
LJP5
72
hr
929 1341 3237 0.4143 0.2260
Hs 578T GDC-0980
3.33
uM
LJP5
72
hr
929 1311 3237 0.4052 0.2109
Hs 578T GDC-0980
10
uM
LJP5
72
hr
929 1198 3237 0.3704 0.1512
Hs 578T Mitoxantrone
0.04
uM
LJP5
72
hr
929 1292 3237 0.3993 0.2006
Hs 578T Mitoxantrone
0.04
uM
LJP6
72
hr
929 1329 3216 0.4131 0.2207
Hs 578T Mitoxantrone
0.12
uM
LJP5
72
hr
929 1017 3237 0.3142 0.0505
Hs 578T Mitoxantrone
0.12
uM
LJP6
72
hr
929 941 3216 0.2927 0.0072
Hs 578T Mitoxantrone
0.37
uM
LJP5
72
hr
929 935 3237 0.2888 0.0032
Hs 578T Mitoxantrone
0.37
uM
LJP6
72
hr
929 894 3216 0.2779 -0.0215
Hs 578T Mitoxantrone
1.11
uM
LJP5
72
hr
929 774 3237 0.2391 -0.0973
Hs 578T Mitoxantrone
1.11
uM
LJP6
72
hr
929 775 3216 0.2407 -0.0987
Hs 578T Mitoxantrone
3.33
uM
LJP5
72
hr
929 530 3237 0.1639 -0.2678
Hs 578T Mitoxantrone
3.33
uM
LJP6
72
hr
929 550 3216 0.1711 -0.2542
Hs 578T Mitoxantrone
10
uM
LJP5
72
hr
929 442 3237 0.1366 -0.3389