LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
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Hs 578T | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 929 | 1593 | 3237 | 0.4922 | 0.3491 |
Hs 578T | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 929 | 1477 | 3216 | 0.4593 | 0.2954 |
Hs 578T | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1374 | 3237 | 0.4245 | 0.2424 |
Hs 578T | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 929 | 1254 | 3216 | 0.3898 | 0.1818 |
Hs 578T | PD0325901 | 10 | uM | LJP5 | 72 | hr | 929 | 1327 | 3237 | 0.4100 | 0.2183 |
Hs 578T | PD0325901 | 10 | uM | LJP6 | 72 | hr | 929 | 1174 | 3216 | 0.3649 | 0.1387 |
Hs 578T | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 929 | 2552 | 3237 | 0.7888 | 0.7530 |
Hs 578T | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 929 | 2701 | 3216 | 0.8399 | 0.8142 |
Hs 578T | Geldanamycin | 0.12 | uM | LJP5 | 72 | hr | 929 | 1445 | 3237 | 0.4466 | 0.2781 |
Hs 578T | Geldanamycin | 0.12 | uM | LJP6 | 72 | hr | 929 | 1412 | 3216 | 0.4390 | 0.2629 |
Hs 578T | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 929 | 1238 | 3237 | 0.3828 | 0.1730 |
Hs 578T | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 929 | 1388 | 3216 | 0.4315 | 0.2510 |
Hs 578T | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 929 | 1275 | 3237 | 0.3941 | 0.1924 |
Hs 578T | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 929 | 1326 | 3216 | 0.4124 | 0.2193 |
Hs 578T | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 929 | 1218 | 3237 | 0.3765 | 0.1625 |
Hs 578T | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 929 | 1315 | 3216 | 0.4088 | 0.2137 |
Hs 578T | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 929 | 1034 | 3237 | 0.3195 | 0.0612 |
Hs 578T | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 929 | 1075 | 3216 | 0.3343 | 0.0844 |
Hs 578T | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3387 | 3237 | 1.0461 | 1.0506 |
Hs 578T | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 929 | 3228 | 3237 | 0.9972 | 0.9970 |
Hs 578T | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 929 | 3251 | 3237 | 1.0044 | 1.0050 |
Hs 578T | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 929 | 2926 | 3237 | 0.9037 | 0.8904 |
Hs 578T | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 929 | 2396 | 3237 | 0.7399 | 0.6911 |
Hs 578T | YM 201636 | 10 | uM | LJP5 | 72 | hr | 929 | 1272 | 3237 | 0.3929 | 0.1904 |
Hs 578T | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3301 | 3237 | 1.0195 | 1.0214 |