LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Erlotinib
10
uM
LJP5
 72
hr
 929 2141 3237 0.6614 0.5896
Hs 578T Gefitinib
0.04
uM
LJP6
 72
hr
 929 3235 3216 1.0056 1.0062
Hs 578T Gefitinib
0.12
uM
LJP6
 72
hr
 929 3182 3216 0.9892 0.9878
Hs 578T Gefitinib
0.37
uM
LJP6
 72
hr
 929 3155 3216 0.9807 0.9783
Hs 578T Gefitinib
1.11
uM
LJP6
 72
hr
 929 3132 3216 0.9736 0.9703
Hs 578T Gefitinib
3.33
uM
LJP6
 72
hr
 929 3184 3216 0.9901 0.9889
Hs 578T Gefitinib
10
uM
LJP6
 72
hr
 929 2747 3216 0.8543 0.8317
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 929 3632 3237 1.1221 1.1321
Hs 578T Nilotinib
0.12
uM
LJP5
 72
hr
 929 3674 3237 1.1348 1.1454
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 929 3705 3237 1.1445 1.1555
Hs 578T Nilotinib
1.11
uM
LJP5
 72
hr
 929 3608 3237 1.1146 1.1241
Hs 578T Nilotinib
3.33
uM
LJP5
 72
hr
 929 3664 3237 1.1321 1.1427
Hs 578T Nilotinib
10
uM
LJP5
 72
hr
 929 1149 3237 0.3554 0.1245
Hs 578T JNK-9L
0.04
uM
LJP6
 72
hr
 929 3333 3216 1.0360 1.0397
Hs 578T JNK-9L
0.12
uM
LJP6
 72
hr
 929 3394 3216 1.0550 1.0605
Hs 578T JNK-9L
0.37
uM
LJP6
 72
hr
 929 2930 3216 0.9111 0.8985
Hs 578T JNK-9L
1.11
uM
LJP6
 72
hr
 929 2328 3216 0.7237 0.6691
Hs 578T JNK-9L
3.33
uM
LJP6
 72
hr
 929 1294 3216 0.4024 0.2028
Hs 578T JNK-9L
10
uM
LJP6
 72
hr
 929 886 3216 0.2754 -0.0270
Hs 578T PD0325901
0.04
uM
LJP5
 72
hr
 929 1821 3237 0.5627 0.4532
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 929 1786 3216 0.5554 0.4401
Hs 578T PD0325901
0.12
uM
LJP5
 72
hr
 929 1708 3237 0.5278 0.4021
Hs 578T PD0325901
0.12
uM
LJP6
 72
hr
 929 1621 3216 0.5040 0.3643
Hs 578T PD0325901
0.37
uM
LJP5
 72
hr
 929 1618 3237 0.5000 0.3607
Hs 578T PD0325901
0.37
uM
LJP6
 72
hr
 929 1591 3216 0.4946 0.3499