LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Brivanib
1.11
uM
LJP5
 72
hr
 929 3039 3237 0.9389 0.9312
Hs 578T Brivanib
3.33
uM
LJP5
 72
hr
 929 3013 3237 0.9308 0.9220
Hs 578T Brivanib
10
uM
LJP5
 72
hr
 929 2759 3237 0.8525 0.8303
Hs 578T CHIR-99021
0.04
uM
LJP6
 72
hr
 929 3117 3216 0.9692 0.9652
Hs 578T CHIR-99021
0.12
uM
LJP6
 72
hr
 929 3128 3216 0.9725 0.9690
Hs 578T CHIR-99021
0.37
uM
LJP6
 72
hr
 929 3086 3216 0.9594 0.9538
Hs 578T CHIR-99021
1.11
uM
LJP6
 72
hr
 929 2926 3216 0.9098 0.8971
Hs 578T CHIR-99021
3.33
uM
LJP6
 72
hr
 929 2965 3216 0.9223 0.9109
Hs 578T CHIR-99021
10
uM
LJP6
 72
hr
 929 1986 3216 0.6174 0.5277
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 929 3168 3216 0.9848 0.9828
Hs 578T Linifanib
0.12
uM
LJP6
 72
hr
 929 3121 3216 0.9704 0.9668
Hs 578T Linifanib
0.37
uM
LJP6
 72
hr
 929 3052 3216 0.9489 0.9421
Hs 578T Linifanib
1.11
uM
LJP6
 72
hr
 929 3133 3216 0.9741 0.9709
Hs 578T Linifanib
3.33
uM
LJP6
 72
hr
 929 3085 3216 0.9593 0.9540
Hs 578T Linifanib
10
uM
LJP6
 72
hr
 929 2426 3216 0.7543 0.7087
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 929 3293 3237 1.0174 1.0193
Hs 578T PIK-93
0.12
uM
LJP5
 72
hr
 929 3328 3237 1.0281 1.0311
Hs 578T PIK-93
0.37
uM
LJP5
 72
hr
 929 3370 3237 1.0411 1.0452
Hs 578T PIK-93
1.11
uM
LJP5
 72
hr
 929 3280 3237 1.0132 1.0146
Hs 578T PIK-93
3.33
uM
LJP5
 72
hr
 929 2309 3237 0.7135 0.6581
Hs 578T PIK-93
10
uM
LJP5
 72
hr
 929 1354 3237 0.4185 0.2329
Hs 578T Dactolisib
0.04
uM
LJP5
 72
hr
 929 1562 3237 0.4827 0.3345
Hs 578T Dactolisib
0.12
uM
LJP5
 72
hr
 929 1462 3237 0.4518 0.2861
Hs 578T Dactolisib
0.37
uM
LJP5
 72
hr
 929 1307 3237 0.4038 0.2086
Hs 578T Dactolisib
1.11
uM
LJP5
 72
hr
 929 1360 3237 0.4202 0.2356