LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD8330
0.37
uM
LJP5
 72
hr
 929 1571 3237 0.4851 0.3379
Hs 578T AZD8330
1.11
uM
LJP5
 72
hr
 929 1571 3237 0.4853 0.3385
Hs 578T AZD8330
3.33
uM
LJP5
 72
hr
 929 1544 3237 0.4768 0.3251
Hs 578T AZD8330
10
uM
LJP5
 72
hr
 929 1511 3237 0.4667 0.3097
Hs 578T TGX221
0.04
uM
LJP5
 72
hr
 929 3021 3237 0.9329 0.9240
Hs 578T TGX221
0.12
uM
LJP5
 72
hr
 929 2824 3237 0.8719 0.8517
Hs 578T TGX221
0.37
uM
LJP5
 72
hr
 929 2964 3237 0.9155 0.9041
Hs 578T TGX221
1.11
uM
LJP5
 72
hr
 929 2949 3237 0.9108 0.8987
Hs 578T TGX221
3.33
uM
LJP5
 72
hr
 929 1825 3237 0.5639 0.4549
Hs 578T TGX221
10
uM
LJP5
 72
hr
 929 2401 3237 0.7413 0.6921
Hs 578T GSK1059615
0.04
uM
LJP5
 72
hr
 929 3168 3237 0.9788 0.9764
Hs 578T GSK1059615
0.04
uM
LJP6
 72
hr
 929 2974 3216 0.9245 0.9142
Hs 578T GSK1059615
0.12
uM
LJP5
 72
hr
 929 2877 3237 0.8889 0.8733
Hs 578T GSK1059615
0.12
uM
LJP6
 72
hr
 929 2554 3216 0.7939 0.7580
Hs 578T GSK1059615
0.37
uM
LJP5
 72
hr
 929 2192 3237 0.6771 0.6106
Hs 578T GSK1059615
0.37
uM
LJP6
 72
hr
 929 2053 3216 0.6382 0.5563
Hs 578T GSK1059615
1.11
uM
LJP5
 72
hr
 929 1568 3237 0.4844 0.3370
Hs 578T GSK1059615
1.11
uM
LJP6
 72
hr
 929 1629 3216 0.5064 0.3678
Hs 578T GSK1059615
3.33
uM
LJP5
 72
hr
 929 1057 3237 0.3266 0.0740
Hs 578T GSK1059615
3.33
uM
LJP6
 72
hr
 929 1302 3216 0.4049 0.2071
Hs 578T GSK1059615
10
uM
LJP5
 72
hr
 929 887 3237 0.2741 -0.0255
Hs 578T GSK1059615
10
uM
LJP6
 72
hr
 929 852 3216 0.2648 -0.0488
Hs 578T Brivanib
0.04
uM
LJP5
 72
hr
 929 3078 3237 0.9510 0.9450
Hs 578T Brivanib
0.12
uM
LJP5
 72
hr
 929 3076 3237 0.9505 0.9444
Hs 578T Brivanib
0.37
uM
LJP5
 72
hr
 929 3101 3237 0.9580 0.9530