LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Foretinib
0.12
uM
LJP5
 72
hr
 929 2832 3237 0.8748 0.8568
Hs 578T Foretinib
0.37
uM
LJP5
 72
hr
 929 2054 3237 0.6345 0.5533
Hs 578T Foretinib
1.11
uM
LJP5
 72
hr
 929 1682 3237 0.5197 0.3904
Hs 578T Foretinib
3.33
uM
LJP5
 72
hr
 929 1491 3237 0.4605 0.2994
Hs 578T Foretinib
10
uM
LJP5
 72
hr
 929 697 3237 0.2153 -0.1489
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 929 2947 3216 0.9162 0.9044
Hs 578T AZD 5438
0.12
uM
LJP6
 72
hr
 929 2372 3216 0.7378 0.6877
Hs 578T AZD 5438
0.37
uM
LJP6
 72
hr
 929 1482 3216 0.4608 0.2975
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 929 1009 3216 0.3138 0.0464
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 929 941 3216 0.2924 0.0046
Hs 578T AZD 5438
10
uM
LJP6
 72
hr
 929 786 3216 0.2446 -0.0891
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 929 3215 3237 0.9932 0.9925
Hs 578T Pelitinib
0.12
uM
LJP5
 72
hr
 929 3189 3237 0.9850 0.9832
Hs 578T Pelitinib
0.37
uM
LJP5
 72
hr
 929 2918 3237 0.9017 0.8883
Hs 578T Pelitinib
1.11
uM
LJP5
 72
hr
 929 2716 3237 0.8392 0.8145
Hs 578T Pelitinib
3.33
uM
LJP5
 72
hr
 929 2891 3237 0.8933 0.8786
Hs 578T Pelitinib
10
uM
LJP5
 72
hr
 929 718 3237 0.2220 -0.1334
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 929 1342 3237 0.4145 0.2260
Hs 578T Luminespib
0.12
uM
LJP5
 72
hr
 929 1326 3237 0.4095 0.2181
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 929 1311 3237 0.4050 0.2105
Hs 578T Luminespib
1.11
uM
LJP5
 72
hr
 929 1358 3237 0.4195 0.2345
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 929 1350 3237 0.4172 0.2303
Hs 578T Luminespib
10
uM
LJP5
 72
hr
 929 1302 3237 0.4023 0.2062
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 929 1531 3237 0.4730 0.3190
Hs 578T AZD8330
0.12
uM
LJP5
 72
hr
 929 1482 3237 0.4577 0.2957