LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Buparlisib
0.04
uM
LJP5
 72
hr
 929 3189 3237 0.9852 0.9834
Hs 578T Buparlisib
0.12
uM
LJP5
 72
hr
 929 2881 3237 0.8903 0.8750
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 929 2477 3237 0.7651 0.7231
Hs 578T Buparlisib
1.11
uM
LJP5
 72
hr
 929 1390 3237 0.4293 0.2499
Hs 578T Buparlisib
3.33
uM
LJP5
 72
hr
 929 761 3237 0.2349 -0.1073
Hs 578T Buparlisib
10
uM
LJP5
 72
hr
 929 657 3237 0.2028 -0.1778
Hs 578T XL147
0.04
uM
LJP5
 72
hr
 929 3301 3237 1.0199 1.0220
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 929 3292 3237 1.0171 1.0188
Hs 578T XL147
0.37
uM
LJP5
 72
hr
 929 3202 3237 0.9893 0.9881
Hs 578T XL147
1.11
uM
LJP5
 72
hr
 929 3216 3237 0.9936 0.9928
Hs 578T XL147
3.33
uM
LJP5
 72
hr
 929 3025 3237 0.9345 0.9262
Hs 578T XL147
10
uM
LJP5
 72
hr
 929 2805 3237 0.8666 0.8471
Hs 578T Y39983
0.04
uM
LJP6
 72
hr
 929 2906 3216 0.9033 0.8895
Hs 578T Y39983
0.12
uM
LJP6
 72
hr
 929 2577 3216 0.8013 0.7674
Hs 578T Y39983
0.37
uM
LJP6
 72
hr
 929 2606 3216 0.8104 0.7786
Hs 578T Y39983
1.11
uM
LJP6
 72
hr
 929 2493 3216 0.7749 0.7345
Hs 578T Y39983
3.33
uM
LJP6
 72
hr
 929 2102 3216 0.6536 0.5773
Hs 578T Y39983
10
uM
LJP6
 72
hr
 929 1211 3216 0.3765 0.1593
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 929 2947 3216 0.9164 0.9048
Hs 578T Nintedanib
0.12
uM
LJP6
 72
hr
 929 2767 3216 0.8604 0.8389
Hs 578T Nintedanib
0.37
uM
LJP6
 72
hr
 929 2350 3216 0.7304 0.6779
Hs 578T Nintedanib
1.11
uM
LJP6
 72
hr
 929 1755 3216 0.5454 0.4253
Hs 578T Nintedanib
3.33
uM
LJP6
 72
hr
 929 1395 3216 0.4337 0.2544
Hs 578T Nintedanib
10
uM
LJP6
 72
hr
 929 999 3216 0.3104 0.0396
Hs 578T Foretinib
0.04
uM
LJP5
 72
hr
 929 3046 3237 0.9412 0.9339