LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A CGP60474
10
uM
LJP6
 72
hr
 513 402 10473 0.0384 -0.0616
MCF 10A PD173074
0.04
uM
LJP6
 72
hr
 513 10923 10473 1.0430 1.0194
MCF 10A PD173074
0.12
uM
LJP6
 72
hr
 513 10571 10473 1.0094 1.0043
MCF 10A PD173074
0.37
uM
LJP6
 72
hr
 513 10522 10473 1.0047 1.0020
MCF 10A PD173074
1.11
uM
LJP6
 72
hr
 513 10484 10473 1.0012 1.0005
MCF 10A PD173074
3.33
uM
LJP6
 72
hr
 513 10543 10473 1.0068 1.0030
MCF 10A PD173074
10
uM
LJP6
 72
hr
 513 2992 10473 0.2857 0.4983
MCF 10A Crizotinib
0.04
uM
LJP5
 72
hr
 513 9680 10362 0.9341 0.9688
MCF 10A Crizotinib
0.12
uM
LJP5
 72
hr
 513 8949 10362 0.8634 0.9324
MCF 10A Crizotinib
0.37
uM
LJP5
 72
hr
 513 8666 10362 0.8363 0.9192
MCF 10A Crizotinib
1.11
uM
LJP5
 72
hr
 513 8099 10362 0.7815 0.8893
MCF 10A Crizotinib
3.33
uM
LJP5
 72
hr
 513 6595 10362 0.6365 0.8012
MCF 10A Crizotinib
10
uM
LJP5
 72
hr
 513 739 10362 0.0713 0.0862
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 513 10692 10473 1.0210 1.0095
MCF 10A BMS345541
0.12
uM
LJP6
 72
hr
 513 10353 10473 0.9886 0.9946
MCF 10A BMS345541
0.37
uM
LJP6
 72
hr
 513 10154 10473 0.9696 0.9858
MCF 10A BMS345541
1.11
uM
LJP6
 72
hr
 513 10065 10473 0.9610 0.9818
MCF 10A BMS345541
3.33
uM
LJP6
 72
hr
 513 9529 10473 0.9097 0.9567
MCF 10A BMS345541
10
uM
LJP6
 72
hr
 513 6788 10473 0.6483 0.8058
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 513 11127 10473 1.0625 1.0279
MCF 10A KIN001-043
0.12
uM
LJP6
 72
hr
 513 10587 10473 1.0108 1.0047
MCF 10A KIN001-043
0.37
uM
LJP6
 72
hr
 513 10145 10473 0.9687 0.9854
MCF 10A KIN001-043
1.11
uM
LJP6
 72
hr
 513 8581 10473 0.8192 0.9100
MCF 10A KIN001-043
3.33
uM
LJP6
 72
hr
 513 6085 10473 0.5809 0.7645
MCF 10A KIN001-043
10
uM
LJP6
 72
hr
 513 1892 10473 0.1807 0.3481