LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WZ3105
3.33
uM
LJP5
 72
hr
 929 839 3237 0.2592 -0.0552
Hs 578T WZ3105
10
uM
LJP5
 72
hr
 929 913 3237 0.2824 -0.0096
Hs 578T XMD11-50
0.04
uM
LJP6
 72
hr
 929 3165 3216 0.9841 0.9823
Hs 578T XMD11-50
0.12
uM
LJP6
 72
hr
 929 3059 3216 0.9513 0.9449
Hs 578T XMD11-50
0.37
uM
LJP6
 72
hr
 929 2719 3216 0.8454 0.8210
Hs 578T XMD11-50
1.11
uM
LJP6
 72
hr
 929 2327 3216 0.7235 0.6695
Hs 578T XMD11-50
3.33
uM
LJP6
 72
hr
 929 1644 3216 0.5112 0.3752
Hs 578T XMD11-50
10
uM
LJP6
 72
hr
 929 962 3216 0.2991 0.0195
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 929 3182 3216 0.9894 0.9881
Hs 578T XMD11-85h
0.12
uM
LJP6
 72
hr
 929 3107 3216 0.9659 0.9615
Hs 578T XMD11-85h
0.37
uM
LJP6
 72
hr
 929 3006 3216 0.9348 0.9260
Hs 578T XMD11-85h
1.11
uM
LJP6
 72
hr
 929 2949 3216 0.9170 0.9056
Hs 578T XMD11-85h
3.33
uM
LJP6
 72
hr
 929 2808 3216 0.8730 0.8538
Hs 578T XMD11-85h
10
uM
LJP6
 72
hr
 929 1611 3216 0.5006 0.3584
Hs 578T XMD16-144
0.04
uM
LJP5
 72
hr
 929 1812 3237 0.5599 0.4493
Hs 578T XMD16-144
0.12
uM
LJP5
 72
hr
 929 1375 3237 0.4249 0.2432
Hs 578T XMD16-144
0.37
uM
LJP5
 72
hr
 929 1400 3237 0.4328 0.2560
Hs 578T XMD16-144
1.11
uM
LJP5
 72
hr
 929 1318 3237 0.4070 0.2138
Hs 578T XMD16-144
3.33
uM
LJP5
 72
hr
 929 1009 3237 0.3117 0.0468
Hs 578T XMD16-144
10
uM
LJP5
 72
hr
 929 832 3237 0.2569 -0.0605
Hs 578T Erlotinib
0.04
uM
LJP5
 72
hr
 929 3145 3237 0.9717 0.9683
Hs 578T Erlotinib
0.12
uM
LJP5
 72
hr
 929 3071 3237 0.9489 0.9426
Hs 578T Erlotinib
0.37
uM
LJP5
 72
hr
 929 3071 3237 0.9488 0.9424
Hs 578T Erlotinib
1.11
uM
LJP5
 72
hr
 929 3059 3237 0.9453 0.9385
Hs 578T Erlotinib
3.33
uM
LJP5
 72
hr
 929 2989 3237 0.9234 0.9133