LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Saracatinib
0.04
uM
LJP6
 72
hr
 513 10896 10473 1.0404 1.0182
MCF 10A Saracatinib
0.12
uM
LJP6
 72
hr
 513 9681 10473 0.9243 0.9632
MCF 10A Saracatinib
0.37
uM
LJP6
 72
hr
 513 7574 10473 0.7231 0.8560
MCF 10A Saracatinib
1.11
uM
LJP6
 72
hr
 513 4140 10473 0.3951 0.6147
MCF 10A Saracatinib
3.33
uM
LJP6
 72
hr
 513 2037 10473 0.1945 0.3724
MCF 10A Saracatinib
10
uM
LJP6
 72
hr
 513 716 10473 0.0684 0.0796
MCF 10A Sigma A6730
0.04
uM
LJP5
 72
hr
 513 9985 10362 0.9636 0.9830
MCF 10A Sigma A6730
0.12
uM
LJP5
 72
hr
 513 9681 10362 0.9341 0.9687
MCF 10A Sigma A6730
0.37
uM
LJP5
 72
hr
 513 9545 10362 0.9210 0.9624
MCF 10A Sigma A6730
1.11
uM
LJP5
 72
hr
 513 7710 10362 0.7439 0.8679
MCF 10A Sigma A6730
3.33
uM
LJP5
 72
hr
 513 8297 10362 0.8003 0.8988
MCF 10A Sigma A6730
10
uM
LJP5
 72
hr
 513 2423 10362 0.2337 0.4281
MCF 10A WH-4-025
0.04
uM
LJP5
 72
hr
 513 10673 10362 1.0305 1.0133
MCF 10A WH-4-025
0.12
uM
LJP5
 72
hr
 513 7014 10362 0.6771 0.8275
MCF 10A WH-4-025
0.37
uM
LJP5
 72
hr
 513 5345 10362 0.5157 0.7159
MCF 10A WH-4-025
1.11
uM
LJP5
 72
hr
 513 1897 10362 0.1832 0.3469
MCF 10A WH-4-025
3.33
uM
LJP5
 72
hr
 513 1148 10362 0.1109 0.2020
MCF 10A WH-4-025
10
uM
LJP5
 72
hr
 513 882 10362 0.0851 0.1325
MCF 10A R406
0.04
uM
LJP6
 72
hr
 513 9273 10473 0.8854 0.9447
MCF 10A R406
0.12
uM
LJP6
 72
hr
 513 9549 10473 0.9118 0.9578
MCF 10A R406
0.37
uM
LJP6
 72
hr
 513 8786 10473 0.8389 0.9202
MCF 10A R406
1.11
uM
LJP6
 72
hr
 513 7188 10473 0.6861 0.8332
MCF 10A R406
3.33
uM
LJP6
 72
hr
 513 5300 10473 0.5062 0.7085
MCF 10A R406
10
uM
LJP6
 72
hr
 513 3361 10473 0.3208 0.5342
MCF 10A BI-2536
0.04
uM
LJP6
 72
hr
 513 739 10473 0.0706 0.0871