LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T CGP60474
0.04
uM
LJP6
 72
hr
 929 818 3216 0.2543 -0.0696
Hs 578T CGP60474
0.12
uM
LJP5
 72
hr
 929 1323 3237 0.4086 0.2164
Hs 578T CGP60474
0.12
uM
LJP6
 72
hr
 929 808 3216 0.2515 -0.0747
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 929 837 3237 0.2586 -0.0572
Hs 578T CGP60474
0.37
uM
LJP6
 72
hr
 929 849 3216 0.2640 -0.0494
Hs 578T CGP60474
1.11
uM
LJP5
 72
hr
 929 837 3237 0.2587 -0.0567
Hs 578T CGP60474
1.11
uM
LJP6
 72
hr
 929 780 3216 0.2425 -0.0933
Hs 578T CGP60474
3.33
uM
LJP5
 72
hr
 929 942 3237 0.2913 0.0073
Hs 578T CGP60474
3.33
uM
LJP6
 72
hr
 929 734 3216 0.2282 -0.1244
Hs 578T CGP60474
10
uM
LJP5
 72
hr
 929 788 3237 0.2435 -0.0879
Hs 578T CGP60474
10
uM
LJP6
 72
hr
 929 669 3216 0.2081 -0.1674
Hs 578T PD173074
0.04
uM
LJP6
 72
hr
 929 2861 3216 0.8896 0.8735
Hs 578T PD173074
0.12
uM
LJP6
 72
hr
 929 2842 3216 0.8836 0.8663
Hs 578T PD173074
0.37
uM
LJP6
 72
hr
 929 2869 3216 0.8920 0.8763
Hs 578T PD173074
1.11
uM
LJP6
 72
hr
 929 2904 3216 0.9031 0.8894
Hs 578T PD173074
3.33
uM
LJP6
 72
hr
 929 2877 3216 0.8944 0.8792
Hs 578T PD173074
10
uM
LJP6
 72
hr
 929 1530 3216 0.4756 0.3204
Hs 578T Crizotinib
0.04
uM
LJP5
 72
hr
 929 3151 3237 0.9735 0.9703
Hs 578T Crizotinib
0.12
uM
LJP5
 72
hr
 929 3214 3237 0.9930 0.9923
Hs 578T Crizotinib
0.37
uM
LJP5
 72
hr
 929 2987 3237 0.9228 0.9126
Hs 578T Crizotinib
1.11
uM
LJP5
 72
hr
 929 2815 3237 0.8695 0.8506
Hs 578T Crizotinib
3.33
uM
LJP5
 72
hr
 929 1964 3237 0.6069 0.5154
Hs 578T Crizotinib
10
uM
LJP5
 72
hr
 929 1081 3237 0.3342 0.0875
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 929 3254 3216 1.0119 1.0132
Hs 578T BMS345541
0.12
uM
LJP6
 72
hr
 929 3259 3216 1.0132 1.0144