LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Y39983
1.11
uM
LJP6
 72
hr
 1657 4677 5383 0.8690 0.8415
BT-20 Y39983
3.33
uM
LJP6
 72
hr
 1657 4304 5383 0.7999 0.7537
BT-20 Y39983
10
uM
LJP6
 72
hr
 1657 2245 5383 0.4168 0.1941
BT-20 Nintedanib
0.04
uM
LJP6
 72
hr
 1657 5730 5383 1.0648 1.0755
BT-20 Nintedanib
0.12
uM
LJP6
 72
hr
 1657 5735 5383 1.0657 1.0767
BT-20 Nintedanib
0.37
uM
LJP6
 72
hr
 1657 5330 5383 0.9903 0.9889
BT-20 Nintedanib
1.11
uM
LJP6
 72
hr
 1657 4810 5383 0.8940 0.8723
BT-20 Nintedanib
3.33
uM
LJP6
 72
hr
 1657 4432 5383 0.8231 0.7832
BT-20 Nintedanib
10
uM
LJP6
 72
hr
 1657 3332 5383 0.6188 0.5071
BT-20 Foretinib
0.04
uM
LJP5
 72
hr
 1657 5724 5588 1.0245 1.0279
BT-20 Foretinib
0.12
uM
LJP5
 72
hr
 1657 4719 5588 0.8446 0.8163
BT-20 Foretinib
0.37
uM
LJP5
 72
hr
 1657 3174 5588 0.5681 0.4478
BT-20 Foretinib
1.11
uM
LJP5
 72
hr
 1657 1764 5588 0.3158 0.0363
BT-20 Foretinib
3.33
uM
LJP5
 72
hr
 1657 1624 5588 0.2907 -0.0116
BT-20 Foretinib
10
uM
LJP5
 72
hr
 1657 1525 5588 0.2731 -0.0468
BT-20 AZD 5438
0.04
uM
LJP6
 72
hr
 1657 5047 5383 0.9378 0.9260
BT-20 AZD 5438
0.12
uM
LJP6
 72
hr
 1657 3913 5383 0.7271 0.6580
BT-20 AZD 5438
0.37
uM
LJP6
 72
hr
 1657 2629 5383 0.4882 0.3110
BT-20 AZD 5438
1.11
uM
LJP6
 72
hr
 1657 1829 5383 0.3401 0.0598
BT-20 AZD 5438
3.33
uM
LJP6
 72
hr
 1657 1657 5383 0.3076 -0.0015
BT-20 AZD 5438
10
uM
LJP6
 72
hr
 1657 1023 5383 0.1902 -0.2473
BT-20 Pelitinib
0.04
uM
LJP5
 72
hr
 1657 5675 5588 1.0155 1.0176
BT-20 Pelitinib
0.12
uM
LJP5
 72
hr
 1657 5301 5588 0.9488 0.9409
BT-20 Pelitinib
0.37
uM
LJP5
 72
hr
 1657 4531 5588 0.8108 0.7744
BT-20 Pelitinib
1.11
uM
LJP5
 72
hr
 1657 4369 5588 0.7818 0.7378