LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 PHA-793887
10
uM
LJP6
 72
hr
 1657 1369 5383 0.2544 -0.1070
BT-20 QL-X-138
0.04
uM
LJP6
 72
hr
 1657 3961 5383 0.7348 0.6663
BT-20 QL-X-138
0.12
uM
LJP6
 72
hr
 1657 3985 5383 0.7396 0.6736
BT-20 QL-X-138
0.37
uM
LJP6
 72
hr
 1657 3658 5383 0.6790 0.5914
BT-20 QL-X-138
1.11
uM
LJP6
 72
hr
 1657 3161 5383 0.5866 0.4601
BT-20 QL-X-138
3.33
uM
LJP6
 72
hr
 1657 2739 5383 0.5080 0.3410
BT-20 QL-X-138
10
uM
LJP6
 72
hr
 1657 1231 5383 0.2286 -0.1614
BT-20 QL-XII-47
0.04
uM
LJP6
 72
hr
 1657 4749 5383 0.8827 0.8585
BT-20 QL-XII-47
0.12
uM
LJP6
 72
hr
 1657 4361 5383 0.8107 0.7679
BT-20 QL-XII-47
0.37
uM
LJP6
 72
hr
 1657 2976 5383 0.5531 0.4113
BT-20 QL-XII-47
1.11
uM
LJP6
 72
hr
 1657 1728 5383 0.3216 0.0251
BT-20 QL-XII-47
3.33
uM
LJP6
 72
hr
 1657 1317 5383 0.2450 -0.1265
BT-20 QL-XII-47
10
uM
LJP6
 72
hr
 1657 799 5383 0.1487 -0.3496
BT-20 Torin1
0.04
uM
LJP6
 72
hr
 1657 2445 5383 0.4541 0.2562
BT-20 Torin1
0.12
uM
LJP6
 72
hr
 1657 2103 5383 0.3905 0.1494
BT-20 Torin1
0.37
uM
LJP6
 72
hr
 1657 1781 5383 0.3308 0.0427
BT-20 Torin1
1.11
uM
LJP6
 72
hr
 1657 1451 5383 0.2690 -0.0780
BT-20 Torin1
3.33
uM
LJP6
 72
hr
 1657 1240 5383 0.2297 -0.1607
BT-20 Torin1
10
uM
LJP6
 72
hr
 1657 1080 5383 0.2000 -0.2265
BT-20 Torin2
0.04
uM
LJP5
 72
hr
 1657 1731 5588 0.3098 0.0249
BT-20 Torin2
0.12
uM
LJP5
 72
hr
 1657 1522 5588 0.2726 -0.0474
BT-20 Torin2
0.37
uM
LJP5
 72
hr
 1657 1551 5588 0.2778 -0.0386
BT-20 Torin2
1.11
uM
LJP5
 72
hr
 1657 1311 5588 0.2348 -0.1255
BT-20 Torin2
3.33
uM
LJP5
 72
hr
 1657 1050 5588 0.1880 -0.2295
BT-20 Torin2
10
uM
LJP5
 72
hr
 1657 1242 5588 0.2225 -0.1532