LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T BMS345541
0.37
uM
LJP6
 72
hr
 929 3259 3216 1.0130 1.0140
Hs 578T BMS345541
1.11
uM
LJP6
 72
hr
 929 3115 3216 0.9684 0.9645
Hs 578T BMS345541
3.33
uM
LJP6
 72
hr
 929 2612 3216 0.8120 0.7800
Hs 578T BMS345541
10
uM
LJP6
 72
hr
 929 804 3216 0.2503 -0.0775
Hs 578T KIN001-043
0.04
uM
LJP6
 72
hr
 929 3342 3216 1.0390 1.0431
Hs 578T KIN001-043
0.12
uM
LJP6
 72
hr
 929 3353 3216 1.0426 1.0472
Hs 578T KIN001-043
0.37
uM
LJP6
 72
hr
 929 3379 3216 1.0505 1.0556
Hs 578T KIN001-043
1.11
uM
LJP6
 72
hr
 929 3310 3216 1.0289 1.0320
Hs 578T KIN001-043
3.33
uM
LJP6
 72
hr
 929 3092 3216 0.9614 0.9564
Hs 578T KIN001-043
10
uM
LJP6
 72
hr
 929 1794 3216 0.5576 0.4434
Hs 578T Saracatinib
0.04
uM
LJP6
 72
hr
 929 3166 3216 0.9844 0.9825
Hs 578T Saracatinib
0.12
uM
LJP6
 72
hr
 929 2885 3216 0.8971 0.8824
Hs 578T Saracatinib
0.37
uM
LJP6
 72
hr
 929 2606 3216 0.8102 0.7782
Hs 578T Saracatinib
1.11
uM
LJP6
 72
hr
 929 2202 3216 0.6847 0.6188
Hs 578T Saracatinib
3.33
uM
LJP6
 72
hr
 929 1991 3216 0.6191 0.5302
Hs 578T Saracatinib
10
uM
LJP6
 72
hr
 929 1622 3216 0.5044 0.3648
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 929 3170 3237 0.9794 0.9769
Hs 578T Sigma A6730
0.12
uM
LJP5
 72
hr
 929 3129 3237 0.9668 0.9629
Hs 578T Sigma A6730
0.37
uM
LJP5
 72
hr
 929 3035 3237 0.9376 0.9298
Hs 578T Sigma A6730
1.11
uM
LJP5
 72
hr
 929 2906 3237 0.8979 0.8838
Hs 578T Sigma A6730
3.33
uM
LJP5
 72
hr
 929 2933 3237 0.9062 0.8936
Hs 578T Sigma A6730
10
uM
LJP5
 72
hr
 929 1741 3237 0.5381 0.4176
Hs 578T WH-4-025
0.04
uM
LJP5
 72
hr
 929 3269 3237 1.0099 1.0111
Hs 578T WH-4-025
0.12
uM
LJP5
 72
hr
 929 2335 3237 0.7216 0.6681
Hs 578T WH-4-025
0.37
uM
LJP5
 72
hr
 929 2013 3237 0.6219 0.5362