LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
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Hs 578T | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 929 | 1213 | 3237 | 0.3746 | 0.1587 |
Hs 578T | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 929 | 1092 | 3237 | 0.3375 | 0.0924 |
Hs 578T | WH-4-025 | 10 | uM | LJP5 | 72 | hr | 929 | 617 | 3237 | 0.1904 | -0.2084 |
Hs 578T | R406 | 0.04 | uM | LJP6 | 72 | hr | 929 | 3133 | 3216 | 0.9742 | 0.9711 |
Hs 578T | R406 | 0.12 | uM | LJP6 | 72 | hr | 929 | 2945 | 3216 | 0.9157 | 0.9040 |
Hs 578T | R406 | 0.37 | uM | LJP6 | 72 | hr | 929 | 2781 | 3216 | 0.8646 | 0.8438 |
Hs 578T | R406 | 1.11 | uM | LJP6 | 72 | hr | 929 | 2614 | 3216 | 0.8128 | 0.7814 |
Hs 578T | R406 | 3.33 | uM | LJP6 | 72 | hr | 929 | 2188 | 3216 | 0.6803 | 0.6130 |
Hs 578T | R406 | 10 | uM | LJP6 | 72 | hr | 929 | 1322 | 3216 | 0.4111 | 0.2173 |
Hs 578T | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 929 | 899 | 3216 | 0.2799 | -0.0184 |
Hs 578T | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 929 | 946 | 3216 | 0.2943 | 0.0100 |
Hs 578T | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 929 | 945 | 3216 | 0.2941 | 0.0097 |
Hs 578T | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 929 | 982 | 3216 | 0.3053 | 0.0310 |
Hs 578T | BI-2536 | 3.33 | uM | LJP6 | 72 | hr | 929 | 977 | 3216 | 0.3039 | 0.0286 |
Hs 578T | BI-2536 | 10 | uM | LJP6 | 72 | hr | 929 | 991 | 3216 | 0.3083 | 0.0367 |
Hs 578T | A443654 | 0.04 | uM | LJP6 | 72 | hr | 929 | 2096 | 3216 | 0.6517 | 0.5746 |
Hs 578T | A443654 | 0.12 | uM | LJP6 | 72 | hr | 929 | 1547 | 3216 | 0.4809 | 0.3284 |
Hs 578T | A443654 | 0.37 | uM | LJP6 | 72 | hr | 929 | 952 | 3216 | 0.2960 | 0.0135 |
Hs 578T | A443654 | 1.11 | uM | LJP6 | 72 | hr | 929 | 719 | 3216 | 0.2237 | -0.1339 |
Hs 578T | A443654 | 3.33 | uM | LJP6 | 72 | hr | 929 | 638 | 3216 | 0.1983 | -0.1895 |
Hs 578T | A443654 | 10 | uM | LJP6 | 72 | hr | 929 | 684 | 3216 | 0.2125 | -0.1579 |
Hs 578T | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 929 | 3913 | 3237 | 1.2087 | 1.2219 |
Hs 578T | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 929 | 3796 | 3237 | 1.1726 | 1.1849 |
Hs 578T | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 929 | 3785 | 3237 | 1.1691 | 1.1812 |
Hs 578T | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 929 | 3899 | 3237 | 1.2045 | 1.2177 |