LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T TWS119
0.12
uM
LJP5
 72
hr
 929 3201 3237 0.9888 0.9872
Hs 578T TWS119
0.37
uM
LJP5
 72
hr
 929 3175 3237 0.9810 0.9788
Hs 578T TWS119
1.11
uM
LJP5
 72
hr
 929 2872 3237 0.8872 0.8715
Hs 578T TWS119
3.33
uM
LJP5
 72
hr
 929 2570 3237 0.7941 0.7596
Hs 578T TWS119
10
uM
LJP5
 72
hr
 929 1000 3237 0.3094 0.0402
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 929 3161 3237 0.9766 0.9739
Hs 578T PF477736
0.12
uM
LJP5
 72
hr
 929 2266 3237 0.6997 0.6392
Hs 578T PF477736
0.37
uM
LJP5
 72
hr
 929 1377 3237 0.4255 0.2442
Hs 578T PF477736
1.11
uM
LJP5
 72
hr
 929 1210 3237 0.3740 0.1578
Hs 578T PF477736
3.33
uM
LJP5
 72
hr
 929 1120 3237 0.3463 0.1097
Hs 578T PF477736
10
uM
LJP5
 72
hr
 929 1036 3237 0.3200 0.0615
Hs 578T LDN-193189
0.04
uM
LJP5
 72
hr
 929 3117 3237 0.9628 0.9583
Hs 578T LDN-193189
0.12
uM
LJP5
 72
hr
 929 3017 3237 0.9318 0.9229
Hs 578T LDN-193189
0.37
uM
LJP5
 72
hr
 929 2947 3237 0.9103 0.8981
Hs 578T LDN-193189
1.11
uM
LJP5
 72
hr
 929 3019 3237 0.9324 0.9233
Hs 578T LDN-193189
3.33
uM
LJP5
 72
hr
 929 2511 3237 0.7756 0.7361
Hs 578T LDN-193189
10
uM
LJP5
 72
hr
 929 515 3237 0.1595 -0.2808
Hs 578T PF431396
0.04
uM
LJP5
 72
hr
 929 2578 3237 0.7965 0.7626
Hs 578T PF431396
0.12
uM
LJP5
 72
hr
 929 2458 3237 0.7594 0.7165
Hs 578T PF431396
0.37
uM
LJP5
 72
hr
 929 2177 3237 0.6728 0.6048
Hs 578T PF431396
1.11
uM
LJP5
 72
hr
 929 1588 3237 0.4907 0.3467
Hs 578T PF431396
3.33
uM
LJP5
 72
hr
 929 1369 3237 0.4229 0.2399
Hs 578T PF431396
10
uM
LJP5
 72
hr
 929 873 3237 0.2696 -0.0344
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 929 3393 3216 1.0549 1.0606
Hs 578T Celastrol
0.12
uM
LJP6
 72
hr
 929 3435 3216 1.0682 1.0751