LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PHA-793887
0.04
uM
LJP6
 72
hr
 513 1245 10473 0.1188 0.2233
MCF 10A PHA-793887
0.12
uM
LJP6
 72
hr
 513 1086 10473 0.1037 0.1868
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 513 745 10473 0.0712 0.0883
MCF 10A PHA-793887
1.11
uM
LJP6
 72
hr
 513 611 10473 0.0583 0.0406
MCF 10A PHA-793887
3.33
uM
LJP6
 72
hr
 513 511 10473 0.0488 -0.0020
MCF 10A PHA-793887
10
uM
LJP6
 72
hr
 513 567 10473 0.0541 0.0228
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 513 9244 10473 0.8826 0.9433
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 513 8468 10473 0.8084 0.9037
MCF 10A QL-X-138
0.37
uM
LJP6
 72
hr
 513 5540 10473 0.5291 0.7276
MCF 10A QL-X-138
1.11
uM
LJP6
 72
hr
 513 4231 10473 0.4039 0.6229
MCF 10A QL-X-138
3.33
uM
LJP6
 72
hr
 513 1712 10473 0.1634 0.3168
MCF 10A QL-X-138
10
uM
LJP6
 72
hr
 513 363 10473 0.0347 -0.0771
MCF 10A QL-XII-47
0.04
uM
LJP6
 72
hr
 513 9369 10473 0.8945 0.9492
MCF 10A QL-XII-47
0.12
uM
LJP6
 72
hr
 513 9154 10473 0.8742 0.9389
MCF 10A QL-XII-47
0.37
uM
LJP6
 72
hr
 513 5964 10473 0.5696 0.7570
MCF 10A QL-XII-47
1.11
uM
LJP6
 72
hr
 513 2267 10473 0.2164 0.4056
MCF 10A QL-XII-47
3.33
uM
LJP6
 72
hr
 513 818 10473 0.0781 0.1122
MCF 10A QL-XII-47
10
uM
LJP6
 72
hr
 513 567 10473 0.0541 0.0224
MCF 10A Torin1
0.04
uM
LJP6
 72
hr
 513 2067 10473 0.1973 0.3759
MCF 10A Torin1
0.12
uM
LJP6
 72
hr
 513 1397 10473 0.1334 0.2583
MCF 10A Torin1
0.37
uM
LJP6
 72
hr
 513 1114 10473 0.1064 0.1945
MCF 10A Torin1
1.11
uM
LJP6
 72
hr
 513 1111 10473 0.1061 0.1900
MCF 10A Torin1
3.33
uM
LJP6
 72
hr
 513 944 10473 0.0902 0.1497
MCF 10A Torin1
10
uM
LJP6
 72
hr
 513 863 10473 0.0825 0.1221
MCF 10A Torin2
0.04
uM
LJP5
 72
hr
 513 818 10362 0.0791 0.1079