LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A XL147
3.33
uM
LJP5
 72
hr
 513 9161 10362 0.8840 0.9438
MCF 10A XL147
10
uM
LJP5
 72
hr
 513 4774 10362 0.4604 0.6713
MCF 10A Y39983
0.04
uM
LJP6
 72
hr
 513 9617 10473 0.9183 0.9612
MCF 10A Y39983
0.12
uM
LJP6
 72
hr
 513 7200 10473 0.6875 0.8348
MCF 10A Y39983
0.37
uM
LJP6
 72
hr
 513 7611 10473 0.7267 0.8584
MCF 10A Y39983
1.11
uM
LJP6
 72
hr
 513 7021 10473 0.6704 0.8243
MCF 10A Y39983
3.33
uM
LJP6
 72
hr
 513 5400 10473 0.5154 0.7168
MCF 10A Y39983
10
uM
LJP6
 72
hr
 513 1133 10473 0.1082 0.1992
MCF 10A Nintedanib
0.04
uM
LJP6
 72
hr
 513 10876 10473 1.0384 1.0171
MCF 10A Nintedanib
0.12
uM
LJP6
 72
hr
 513 10367 10473 0.9898 0.9952
MCF 10A Nintedanib
0.37
uM
LJP6
 72
hr
 513 10390 10473 0.9921 0.9963
MCF 10A Nintedanib
1.11
uM
LJP6
 72
hr
 513 10459 10473 0.9986 0.9993
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 513 7959 10473 0.7599 0.8776
MCF 10A Nintedanib
10
uM
LJP6
 72
hr
 513 9040 10473 0.8632 0.9335
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 513 11133 10362 1.0743 1.0333
MCF 10A Foretinib
0.12
uM
LJP5
 72
hr
 513 10269 10362 0.9911 0.9959
MCF 10A Foretinib
0.37
uM
LJP5
 72
hr
 513 8179 10362 0.7895 0.8938
MCF 10A Foretinib
1.11
uM
LJP5
 72
hr
 513 2122 10362 0.2048 0.3872
MCF 10A Foretinib
3.33
uM
LJP5
 72
hr
 513 1147 10362 0.1107 0.2038
MCF 10A Foretinib
10
uM
LJP5
 72
hr
 513 463 10362 0.0447 -0.0245
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 513 9444 10473 0.9018 0.9530
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 513 5533 10473 0.5284 0.7268
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 513 1767 10473 0.1688 0.3277
MCF 10A AZD 5438
1.11
uM
LJP6
 72
hr
 513 579 10473 0.0553 0.0279
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 513 704 10473 0.0672 0.0750