LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
10
uM
LJP6
72
hr
513 576 10473 0.0550 0.0269
MCF 10A Pelitinib
0.04
uM
LJP5
72
hr
513 2132 10362 0.2059 0.3868
MCF 10A Pelitinib
0.12
uM
LJP5
72
hr
513 811 10362 0.0783 0.1111
MCF 10A Pelitinib
0.37
uM
LJP5
72
hr
513 724 10362 0.0699 0.0823
MCF 10A Pelitinib
1.11
uM
LJP5
72
hr
513 767 10362 0.0740 0.0969
MCF 10A Pelitinib
3.33
uM
LJP5
72
hr
513 680 10362 0.0656 0.0654
MCF 10A Pelitinib
10
uM
LJP5
72
hr
513 516 10362 0.0499 0.0010
MCF 10A Luminespib
0.04
uM
LJP5
72
hr
513 474 10362 0.0457 -0.0185
MCF 10A Luminespib
0.12
uM
LJP5
72
hr
513 495 10362 0.0478 -0.0086
MCF 10A Luminespib
0.37
uM
LJP5
72
hr
513 476 10362 0.0459 -0.0176
MCF 10A Luminespib
1.11
uM
LJP5
72
hr
513 465 10362 0.0449 -0.0229
MCF 10A Luminespib
3.33
uM
LJP5
72
hr
513 492 10362 0.0475 -0.0097
MCF 10A Luminespib
10
uM
LJP5
72
hr
513 535 10362 0.0516 0.0095
MCF 10A AZD8330
0.04
uM
LJP5
72
hr
513 447 10362 0.0431 -0.0330
MCF 10A AZD8330
0.12
uM
LJP5
72
hr
513 487 10362 0.0470 -0.0166
MCF 10A AZD8330
0.37
uM
LJP5
72
hr
513 565 10362 0.0545 0.0211
MCF 10A AZD8330
1.11
uM
LJP5
72
hr
513 643 10362 0.0621 0.0532
MCF 10A AZD8330
3.33
uM
LJP5
72
hr
513 652 10362 0.0629 0.0555
MCF 10A AZD8330
10
uM
LJP5
72
hr
513 577 10362 0.0557 0.0274
MCF 10A TGX221
0.04
uM
LJP5
72
hr
513 8988 10362 0.8674 0.9355
MCF 10A TGX221
0.12
uM
LJP5
72
hr
513 8843 10362 0.8532 0.9279
MCF 10A TGX221
0.37
uM
LJP5
72
hr
513 9094 10362 0.8775 0.9405
MCF 10A TGX221
1.11
uM
LJP5
72
hr
513 8824 10362 0.8518 0.9273
MCF 10A TGX221
3.33
uM
LJP5
72
hr
513 1456 10362 0.1407 0.2715
MCF 10A TGX221
10
uM
LJP5
72
hr
513 7674 10362 0.7401 0.8650