LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 513 | 576 | 10473 | 0.0550 | 0.0269 |
MCF 10A | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 513 | 2132 | 10362 | 0.2059 | 0.3868 |
MCF 10A | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 513 | 811 | 10362 | 0.0783 | 0.1111 |
MCF 10A | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 513 | 724 | 10362 | 0.0699 | 0.0823 |
MCF 10A | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 513 | 767 | 10362 | 0.0740 | 0.0969 |
MCF 10A | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 513 | 680 | 10362 | 0.0656 | 0.0654 |
MCF 10A | Pelitinib | 10 | uM | LJP5 | 72 | hr | 513 | 516 | 10362 | 0.0499 | 0.0010 |
MCF 10A | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 513 | 474 | 10362 | 0.0457 | -0.0185 |
MCF 10A | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 513 | 495 | 10362 | 0.0478 | -0.0086 |
MCF 10A | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 513 | 476 | 10362 | 0.0459 | -0.0176 |
MCF 10A | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 513 | 465 | 10362 | 0.0449 | -0.0229 |
MCF 10A | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 513 | 492 | 10362 | 0.0475 | -0.0097 |
MCF 10A | Luminespib | 10 | uM | LJP5 | 72 | hr | 513 | 535 | 10362 | 0.0516 | 0.0095 |
MCF 10A | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 513 | 447 | 10362 | 0.0431 | -0.0330 |
MCF 10A | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 513 | 487 | 10362 | 0.0470 | -0.0166 |
MCF 10A | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 513 | 565 | 10362 | 0.0545 | 0.0211 |
MCF 10A | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 513 | 643 | 10362 | 0.0621 | 0.0532 |
MCF 10A | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 513 | 652 | 10362 | 0.0629 | 0.0555 |
MCF 10A | AZD8330 | 10 | uM | LJP5 | 72 | hr | 513 | 577 | 10362 | 0.0557 | 0.0274 |
MCF 10A | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 513 | 8988 | 10362 | 0.8674 | 0.9355 |
MCF 10A | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 513 | 8843 | 10362 | 0.8532 | 0.9279 |
MCF 10A | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 513 | 9094 | 10362 | 0.8775 | 0.9405 |
MCF 10A | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 513 | 8824 | 10362 | 0.8518 | 0.9273 |
MCF 10A | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 513 | 1456 | 10362 | 0.1407 | 0.2715 |
MCF 10A | TGX221 | 10 | uM | LJP5 | 72 | hr | 513 | 7674 | 10362 | 0.7401 | 0.8650 |