LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Torin2
0.12
uM
LJP5
 72
hr
 513 505 10362 0.0487 -0.0046
MCF 10A Torin2
0.37
uM
LJP5
 72
hr
 513 472 10362 0.0455 -0.0205
MCF 10A Torin2
1.11
uM
LJP5
 72
hr
 513 484 10362 0.0467 -0.0153
MCF 10A Torin2
3.33
uM
LJP5
 72
hr
 513 529 10362 0.0510 0.0055
MCF 10A Torin2
10
uM
LJP5
 72
hr
 513 484 10362 0.0467 -0.0136
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 513 8831 10473 0.8433 0.9232
MCF 10A WZ-4-145
0.12
uM
LJP6
 72
hr
 513 9065 10473 0.8657 0.9347
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 513 8239 10473 0.7867 0.8927
MCF 10A WZ-4-145
1.11
uM
LJP6
 72
hr
 513 5529 10473 0.5277 0.7256
MCF 10A WZ-4-145
3.33
uM
LJP6
 72
hr
 513 4150 10473 0.3961 0.6162
MCF 10A WZ-4-145
10
uM
LJP6
 72
hr
 513 483 10473 0.0461 -0.0145
MCF 10A WZ3105
0.04
uM
LJP5
 72
hr
 513 2104 10362 0.2029 0.3811
MCF 10A WZ3105
0.12
uM
LJP5
 72
hr
 513 759 10362 0.0733 0.0933
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 513 678 10362 0.0653 0.0637
MCF 10A WZ3105
1.11
uM
LJP5
 72
hr
 513 630 10362 0.0608 0.0483
MCF 10A WZ3105
3.33
uM
LJP5
 72
hr
 513 615 10362 0.0594 0.0423
MCF 10A WZ3105
10
uM
LJP5
 72
hr
 513 525 10362 0.0507 0.0048
MCF 10A XMD11-50
0.04
uM
LJP6
 72
hr
 513 9828 10473 0.9384 0.9708
MCF 10A XMD11-50
0.12
uM
LJP6
 72
hr
 513 9163 10473 0.8747 0.9388
MCF 10A XMD11-50
0.37
uM
LJP6
 72
hr
 513 7006 10473 0.6688 0.8230
MCF 10A XMD11-50
1.11
uM
LJP6
 72
hr
 513 4147 10473 0.3961 0.6160
MCF 10A XMD11-50
3.33
uM
LJP6
 72
hr
 513 1574 10473 0.1503 0.2937
MCF 10A XMD11-50
10
uM
LJP6
 72
hr
 513 931 10473 0.0889 0.1466
MCF 10A XMD11-85h
0.04
uM
LJP6
 72
hr
 513 9036 10473 0.8631 0.9332
MCF 10A XMD11-85h
0.12
uM
LJP6
 72
hr
 513 8939 10473 0.8537 0.9285