LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Neratinib
1.11
uM
LJP5
 72
hr
 513 712 10362 0.0688 0.0762
MCF 10A Neratinib
3.33
uM
LJP5
 72
hr
 513 683 10362 0.0659 0.0680
MCF 10A Neratinib
10
uM
LJP5
 72
hr
 513 664 10362 0.0640 0.0595
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 513 9324 10473 0.8905 0.9473
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 513 9173 10473 0.8762 0.9394
MCF 10A JW-7-24-1
0.37
uM
LJP6
 72
hr
 513 8077 10473 0.7714 0.8834
MCF 10A JW-7-24-1
1.11
uM
LJP6
 72
hr
 513 6953 10473 0.6641 0.8199
MCF 10A JW-7-24-1
3.33
uM
LJP6
 72
hr
 513 5711 10473 0.5455 0.7397
MCF 10A JW-7-24-1
10
uM
LJP6
 72
hr
 513 604 10473 0.0577 0.0378
MCF 10A Dasatinib
0.04
uM
LJP5
 72
hr
 513 4779 10362 0.4612 0.6727
MCF 10A Dasatinib
0.04
uM
LJP6
 72
hr
 513 1706 10473 0.1629 0.3169
MCF 10A Dasatinib
0.12
uM
LJP5
 72
hr
 513 1768 10362 0.1705 0.3292
MCF 10A Dasatinib
0.12
uM
LJP6
 72
hr
 513 741 10473 0.0708 0.0875
MCF 10A Dasatinib
0.37
uM
LJP5
 72
hr
 513 792 10362 0.0764 0.1048
MCF 10A Dasatinib
0.37
uM
LJP6
 72
hr
 513 525 10473 0.0502 0.0043
MCF 10A Dasatinib
1.11
uM
LJP5
 72
hr
 513 654 10362 0.0631 0.0526
MCF 10A Dasatinib
1.11
uM
LJP6
 72
hr
 513 410 10473 0.0392 -0.0505
MCF 10A Dasatinib
3.33
uM
LJP5
 72
hr
 513 337 10362 0.0325 -0.0932
MCF 10A Dasatinib
3.33
uM
LJP6
 72
hr
 513 305 10473 0.0291 -0.1141
MCF 10A Dasatinib
10
uM
LJP5
 72
hr
 513 332 10362 0.0320 -0.0967
MCF 10A Dasatinib
10
uM
LJP6
 72
hr
 513 217 10473 0.0207 -0.1805
MCF 10A Tozasertib
0.04
uM
LJP5
 72
hr
 513 1653 10362 0.1594 0.3083
MCF 10A Tozasertib
0.12
uM
LJP5
 72
hr
 513 1287 10362 0.1243 0.2362
MCF 10A Tozasertib
0.37
uM
LJP5
 72
hr
 513 1079 10362 0.1041 0.1863
MCF 10A Tozasertib
1.11
uM
LJP5
 72
hr
 513 1080 10362 0.1041 0.1855