LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Ruxolitinib
10
uM
LJP5
 72
hr
 929 2421 3237 0.7481 0.7023
Hs 578T Momelotinib
0.04
uM
LJP5
 72
hr
 929 2939 3237 0.9080 0.8954
Hs 578T Momelotinib
0.12
uM
LJP5
 72
hr
 929 2752 3237 0.8503 0.8277
Hs 578T Momelotinib
0.37
uM
LJP5
 72
hr
 929 2528 3237 0.7811 0.7437
Hs 578T Momelotinib
1.11
uM
LJP5
 72
hr
 929 2307 3237 0.7126 0.6567
Hs 578T Momelotinib
3.33
uM
LJP5
 72
hr
 929 1915 3237 0.5915 0.4937
Hs 578T Momelotinib
10
uM
LJP5
 72
hr
 929 1302 3237 0.4025 0.2062
Hs 578T Fedratinib
0.04
uM
LJP5
 72
hr
 929 3318 3237 1.0248 1.0269
Hs 578T Fedratinib
0.12
uM
LJP5
 72
hr
 929 3223 3237 0.9956 0.9948
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 929 2959 3237 0.9141 0.9024
Hs 578T Fedratinib
1.11
uM
LJP5
 72
hr
 929 2462 3237 0.7606 0.7180
Hs 578T Fedratinib
3.33
uM
LJP5
 72
hr
 929 1581 3237 0.4886 0.3434
Hs 578T Fedratinib
10
uM
LJP5
 72
hr
 929 921 3237 0.2846 -0.0050
Hs 578T Trametinib
0.04
uM
LJP5
 72
hr
 929 1525 3237 0.4713 0.3168
Hs 578T Trametinib
0.12
uM
LJP5
 72
hr
 929 1458 3237 0.4507 0.2846
Hs 578T Trametinib
0.37
uM
LJP5
 72
hr
 929 1485 3237 0.4587 0.2972
Hs 578T Trametinib
1.11
uM
LJP5
 72
hr
 929 1464 3237 0.4525 0.2875
Hs 578T Trametinib
3.33
uM
LJP5
 72
hr
 929 1419 3237 0.4384 0.2651
Hs 578T Trametinib
10
uM
LJP5
 72
hr
 929 1497 3237 0.4628 0.3036
Hs 578T Omipalisib
0.04
uM
LJP6
 72
hr
 929 1409 3216 0.4381 0.2610
Hs 578T Omipalisib
0.12
uM
LJP6
 72
hr
 929 1291 3216 0.4016 0.2017
Hs 578T Omipalisib
0.37
uM
LJP6
 72
hr
 929 1158 3216 0.3597 0.1287
Hs 578T Omipalisib
1.11
uM
LJP6
 72
hr
 929 1005 3216 0.3125 0.0445
Hs 578T Omipalisib
3.33
uM
LJP6
 72
hr
 929 940 3216 0.2925 0.0068
Hs 578T Omipalisib
10
uM
LJP6
 72
hr
 929 862 3216 0.2678 -0.0437