LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SNS-032
3.33
uM
LJP6
 72
hr
 929 795 3216 0.2473 -0.0835
Hs 578T SNS-032
10
uM
LJP6
 72
hr
 929 800 3216 0.2487 -0.0805
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 929 3069 3216 0.9542 0.9483
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 929 3002 3216 0.9333 0.9243
Hs 578T Afatinib
0.37
uM
LJP6
 72
hr
 929 3030 3216 0.9421 0.9342
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 929 2985 3216 0.9281 0.9179
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 929 2740 3216 0.8516 0.8280
Hs 578T Afatinib
10
uM
LJP6
 72
hr
 929 736 3216 0.2290 -0.1226
Hs 578T GSK1904529A
0.04
uM
LJP6
 72
hr
 929 3169 3216 0.9851 0.9832
Hs 578T GSK1904529A
0.12
uM
LJP6
 72
hr
 929 3131 3216 0.9736 0.9703
Hs 578T GSK1904529A
0.37
uM
LJP6
 72
hr
 929 3112 3216 0.9674 0.9629
Hs 578T GSK1904529A
1.11
uM
LJP6
 72
hr
 929 2990 3216 0.9293 0.9193
Hs 578T GSK1904529A
3.33
uM
LJP6
 72
hr
 929 3087 3216 0.9598 0.9545
Hs 578T GSK1904529A
10
uM
LJP6
 72
hr
 929 3070 3216 0.9546 0.9487
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 929 3174 3237 0.9805 0.9783
Hs 578T Linsitinib
0.12
uM
LJP5
 72
hr
 929 3137 3237 0.9691 0.9654
Hs 578T Linsitinib
0.37
uM
LJP5
 72
hr
 929 2995 3237 0.9253 0.9156
Hs 578T Linsitinib
1.11
uM
LJP5
 72
hr
 929 3128 3237 0.9663 0.9622
Hs 578T Linsitinib
3.33
uM
LJP5
 72
hr
 929 3132 3237 0.9674 0.9634
Hs 578T Linsitinib
10
uM
LJP5
 72
hr
 929 2646 3237 0.8174 0.7881
Hs 578T Ruxolitinib
0.04
uM
LJP5
 72
hr
 929 3198 3237 0.9880 0.9867
Hs 578T Ruxolitinib
0.12
uM
LJP5
 72
hr
 929 3239 3237 1.0005 1.0006
Hs 578T Ruxolitinib
0.37
uM
LJP5
 72
hr
 929 3162 3237 0.9770 0.9743
Hs 578T Ruxolitinib
1.11
uM
LJP5
 72
hr
 929 3092 3237 0.9552 0.9497
Hs 578T Ruxolitinib
3.33
uM
LJP5
 72
hr
 929 2948 3237 0.9109 0.8990