LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 513 2003 10473 0.1913 0.3672
MCF 10A GW843682X
1.11
uM
LJP6
 72
hr
 513 732 10473 0.0699 0.0847
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 513 701 10473 0.0669 0.0735
MCF 10A GW843682X
10
uM
LJP6
 72
hr
 513 701 10473 0.0669 0.0723
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 513 9757 10362 0.9414 0.9722
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 513 8387 10362 0.8088 0.9029
MCF 10A HG-5-113-01
0.37
uM
LJP5
 72
hr
 513 6915 10362 0.6671 0.8212
MCF 10A HG-5-113-01
1.11
uM
LJP5
 72
hr
 513 4879 10362 0.4707 0.6805
MCF 10A HG-5-113-01
3.33
uM
LJP5
 72
hr
 513 1445 10362 0.1394 0.2695
MCF 10A HG-5-113-01
10
uM
LJP5
 72
hr
 513 559 10362 0.0540 0.0187
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 513 7496 10473 0.7158 0.8520
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 513 6249 10473 0.5967 0.7760
MCF 10A HG-5-88-01
0.37
uM
LJP6
 72
hr
 513 4095 10473 0.3910 0.6107
MCF 10A HG-5-88-01
1.11
uM
LJP6
 72
hr
 513 3369 10473 0.3217 0.5394
MCF 10A HG-5-88-01
3.33
uM
LJP6
 72
hr
 513 2412 10473 0.2304 0.4263
MCF 10A HG-5-88-01
10
uM
LJP6
 72
hr
 513 1800 10473 0.1720 0.3325
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 513 11110 10473 1.0608 1.0273
MCF 10A HG-6-64-01
0.12
uM
LJP6
 72
hr
 513 10535 10473 1.0061 1.0025
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 513 9226 10473 0.8810 0.9426
MCF 10A HG-6-64-01
1.11
uM
LJP6
 72
hr
 513 5599 10473 0.5347 0.7319
MCF 10A HG-6-64-01
3.33
uM
LJP6
 72
hr
 513 1652 10473 0.1578 0.3079
MCF 10A HG-6-64-01
10
uM
LJP6
 72
hr
 513 246 10473 0.0235 -0.1572
MCF 10A Neratinib
0.04
uM
LJP5
 72
hr
 513 1007 10362 0.0971 0.1663
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 513 766 10362 0.0740 0.0969
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 513 778 10362 0.0751 0.1006