HG-6-64-01 - Small Molecule (ID:10017-101)
| HMS LINCS ID: |
10017-101
|
| Name: | HG-6-64-01 |
| Alternative Names: | KIN001-206 |
| LINCS ID: | LSM-43248 |
| PubChem CID: | |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 577.27 |
| InChi: | InChI=1S/C32H34F3N5O2/c1-4-39-13-15-40(16-14-39)20-25-9-10-26(18-28(25)32(33,34)35)38-31(41)23-6-5-21(2)22(17-23)7-8-24-19-37-30-27(11-12-36-30)29(24)42-3/h5-12,17-19H,4,13-16,20H2,1-3H3,(H,36,37)(H,38,41)/b8-7+ |
| InChi Key: | UMBFDGUGXMOMHX-BQYQJAHWSA-N |
| SMILES: | CC1=CC=C(C(NC2=CC=C(CN3CCN(CC)CC3)C(C(F)(F)F)=C2)=O)C=C1/C=C/C4=C(OC)C5=C(NC=C5)N=C4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ABL1, ABL2, CHUK, CIT, CSF1R, EPHA4, EPHA6, EPHB2, ERBB2, ERBB4, FGFR1, LYN, MAP4K1, MAP4K2, MAPK11, MAPK14, MAPK9, MUSK, PDGFRB, RET, STK10, TAOK3, TEK | |
10 (confirmed non-binding) |
Batch Information for HMSL10017-101-1:
| HMS LINCS Batch ID: | 10017-101-1 |
| Provider: | Nathanael Gray (DFCI) |
| Provider Batch ID: | HG-6-64-01-1 |
| Salt: | 101 |
| Molecular Formula: | C32H34F3N5O2 |
| Molecular Weight: | 577.64 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-04-04 |
(equivalent to 100 nM ≤ Kd < 1µM)