LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Tozasertib
3.33
uM
LJP5
 72
hr
 513 891 10362 0.0859 0.1330
MCF 10A Tozasertib
10
uM
LJP5
 72
hr
 513 824 10362 0.0794 0.1139
MCF 10A Imatinib
0.04
uM
LJP6
 72
hr
 513 10714 10473 1.0230 1.0105
MCF 10A Imatinib
0.12
uM
LJP6
 72
hr
 513 10440 10473 0.9967 0.9983
MCF 10A Imatinib
0.37
uM
LJP6
 72
hr
 513 10451 10473 0.9981 0.9989
MCF 10A Imatinib
1.11
uM
LJP6
 72
hr
 513 10904 10473 1.0413 1.0186
MCF 10A Imatinib
3.33
uM
LJP6
 72
hr
 513 11182 10473 1.0679 1.0302
MCF 10A Imatinib
10
uM
LJP6
 72
hr
 513 11029 10473 1.0531 1.0238
MCF 10A NVP-TAE684
0.04
uM
LJP6
 72
hr
 513 6950 10473 0.6637 0.8200
MCF 10A NVP-TAE684
0.12
uM
LJP6
 72
hr
 513 3340 10473 0.3189 0.5378
MCF 10A NVP-TAE684
0.37
uM
LJP6
 72
hr
 513 2944 10473 0.2811 0.4923
MCF 10A NVP-TAE684
1.11
uM
LJP6
 72
hr
 513 2398 10473 0.2290 0.4237
MCF 10A NVP-TAE684
3.33
uM
LJP6
 72
hr
 513 1472 10473 0.1406 0.2739
MCF 10A NVP-TAE684
10
uM
LJP6
 72
hr
 513 863 10473 0.0824 0.1264
MCF 10A CGP60474
0.04
uM
LJP5
 72
hr
 513 4985 10362 0.4815 0.6884
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 513 542 10473 0.0518 0.0081
MCF 10A CGP60474
0.12
uM
LJP5
 72
hr
 513 677 10362 0.0653 0.0656
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 513 550 10473 0.0526 0.0149
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 513 685 10362 0.0662 0.0689
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 513 572 10473 0.0546 0.0192
MCF 10A CGP60474
1.11
uM
LJP5
 72
hr
 513 694 10362 0.0670 0.0708
MCF 10A CGP60474
1.11
uM
LJP6
 72
hr
 513 497 10473 0.0475 -0.0101
MCF 10A CGP60474
3.33
uM
LJP5
 72
hr
 513 666 10362 0.0643 0.0617
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 513 484 10473 0.0462 -0.0241
MCF 10A CGP60474
10
uM
LJP5
 72
hr
 513 523 10362 0.0505 0.0041