LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A XMD11-85h
0.37
uM
LJP6
 72
hr
 513 9649 10473 0.9213 0.9624
MCF 10A XMD11-85h
1.11
uM
LJP6
 72
hr
 513 9281 10473 0.8862 0.9452
MCF 10A XMD11-85h
3.33
uM
LJP6
 72
hr
 513 8668 10473 0.8277 0.9149
MCF 10A XMD11-85h
10
uM
LJP6
 72
hr
 513 5283 10473 0.5042 0.7075
MCF 10A XMD16-144
0.04
uM
LJP5
 72
hr
 513 8960 10362 0.8647 0.9340
MCF 10A XMD16-144
0.12
uM
LJP5
 72
hr
 513 2848 10362 0.2748 0.4846
MCF 10A XMD16-144
0.37
uM
LJP5
 72
hr
 513 1414 10362 0.1366 0.2632
MCF 10A XMD16-144
1.11
uM
LJP5
 72
hr
 513 1303 10362 0.1257 0.2389
MCF 10A XMD16-144
3.33
uM
LJP5
 72
hr
 513 1297 10362 0.1253 0.2376
MCF 10A XMD16-144
10
uM
LJP5
 72
hr
 513 649 10362 0.0626 0.0534
MCF 10A Erlotinib
0.04
uM
LJP5
 72
hr
 513 9926 10362 0.9578 0.9801
MCF 10A Erlotinib
0.12
uM
LJP5
 72
hr
 513 8611 10362 0.8311 0.9164
MCF 10A Erlotinib
0.37
uM
LJP5
 72
hr
 513 2357 10362 0.2273 0.4198
MCF 10A Erlotinib
1.11
uM
LJP5
 72
hr
 513 626 10362 0.0604 0.0466
MCF 10A Erlotinib
3.33
uM
LJP5
 72
hr
 513 667 10362 0.0643 0.0619
MCF 10A Erlotinib
10
uM
LJP5
 72
hr
 513 773 10362 0.0746 0.0985
MCF 10A Gefitinib
0.04
uM
LJP6
 72
hr
 513 7067 10473 0.6749 0.8271
MCF 10A Gefitinib
0.12
uM
LJP6
 72
hr
 513 2719 10473 0.2597 0.4630
MCF 10A Gefitinib
0.37
uM
LJP6
 72
hr
 513 1020 10473 0.0974 0.1708
MCF 10A Gefitinib
1.11
uM
LJP6
 72
hr
 513 863 10473 0.0824 0.1266
MCF 10A Gefitinib
3.33
uM
LJP6
 72
hr
 513 786 10473 0.0751 0.1014
MCF 10A Gefitinib
10
uM
LJP6
 72
hr
 513 824 10473 0.0787 0.1150
MCF 10A Nilotinib
0.04
uM
LJP5
 72
hr
 513 10927 10362 1.0548 1.0246
MCF 10A Nilotinib
0.12
uM
LJP5
 72
hr
 513 10609 10362 1.0239 1.0109
MCF 10A Nilotinib
0.37
uM
LJP5
 72
hr
 513 9986 10362 0.9639 0.9830